| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACTL9 | CAPZA3 | ENSP00000316674 | ENSP00000326238 | Actin-like protein 9; Actin related proteins | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | 0.662 |
| ACTL9 | PLCZ1 | ENSP00000316674 | ENSP00000266505 | Actin-like protein 9; Actin related proteins | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is [...] | 0.544 |
| ACTL9 | TEX33 | ENSP00000316674 | ENSP00000386118 | Actin-like protein 9; Actin related proteins | Testis-expressed protein 33; Testis expressed 33 | 0.524 |
| ACTL9 | TPPP2 | ENSP00000316674 | ENSP00000317595 | Actin-like protein 9; Actin related proteins | Tubulin polymerization-promoting protein family member 2; May bind tubulin but has no microtubule bundling activity; Tubulin polymerization promoting proteins | 0.512 |
| C20orf197 | PCDHAC2 | ENSP00000316457 | ENSP00000289269 | Uncharacterized protein C20orf197; Chromosome 20 open reading frame 197 | Protocadherin alpha-C2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins | 0.581 |
| C20orf197 | TEX33 | ENSP00000316457 | ENSP00000386118 | Uncharacterized protein C20orf197; Chromosome 20 open reading frame 197 | Testis-expressed protein 33; Testis expressed 33 | 0.589 |
| CAPZA3 | ACTL9 | ENSP00000326238 | ENSP00000316674 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Actin-like protein 9; Actin related proteins | 0.662 |
| CAPZA3 | PLCZ1 | ENSP00000326238 | ENSP00000266505 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is [...] | 0.846 |
| CAPZA3 | TEX33 | ENSP00000326238 | ENSP00000386118 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Testis-expressed protein 33; Testis expressed 33 | 0.635 |
| CAPZA3 | TPPP2 | ENSP00000326238 | ENSP00000317595 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Tubulin polymerization-promoting protein family member 2; May bind tubulin but has no microtubule bundling activity; Tubulin polymerization promoting proteins | 0.529 |
| PCDHAC2 | C20orf197 | ENSP00000289269 | ENSP00000316457 | Protocadherin alpha-C2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins | Uncharacterized protein C20orf197; Chromosome 20 open reading frame 197 | 0.581 |
| PCDHAC2 | TEX33 | ENSP00000289269 | ENSP00000386118 | Protocadherin alpha-C2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins | Testis-expressed protein 33; Testis expressed 33 | 0.536 |
| PLCZ1 | ACTL9 | ENSP00000266505 | ENSP00000316674 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is [...] | Actin-like protein 9; Actin related proteins | 0.544 |
| PLCZ1 | CAPZA3 | ENSP00000266505 | ENSP00000326238 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is [...] | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | 0.846 |
| PLCZ1 | TEX33 | ENSP00000266505 | ENSP00000386118 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is [...] | Testis-expressed protein 33; Testis expressed 33 | 0.511 |
| PLCZ1 | TPPP2 | ENSP00000266505 | ENSP00000317595 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is [...] | Tubulin polymerization-promoting protein family member 2; May bind tubulin but has no microtubule bundling activity; Tubulin polymerization promoting proteins | 0.557 |
| RGAG1 | TEX33 | ENSP00000419786 | ENSP00000386118 | Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1 | Testis-expressed protein 33; Testis expressed 33 | 0.517 |
| SLC17A4 | ST6GALNAC1 | ENSP00000367137 | ENSP00000156626 | Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro); Belongs to the major facilitator superfamily. Sodium/anion cotransporter family | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Sialyltransferases | 0.473 |
| SLC17A4 | TEX33 | ENSP00000367137 | ENSP00000386118 | Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro); Belongs to the major facilitator superfamily. Sodium/anion cotransporter family | Testis-expressed protein 33; Testis expressed 33 | 0.532 |
| ST6GALNAC1 | SLC17A4 | ENSP00000156626 | ENSP00000367137 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Sialyltransferases | Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro); Belongs to the major facilitator superfamily. Sodium/anion cotransporter family | 0.473 |
