| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C17orf53 | DCDC1 | ENSP00000313500 | ENSP00000385936 | Uncharacterized protein C17orf53; Chromosome 17 open reading frame 53 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | 0.588 |
| C17orf53 | STARD3NL | ENSP00000313500 | ENSP00000009041 | Uncharacterized protein C17orf53; Chromosome 17 open reading frame 53 | STARD3 N-terminal-like protein; Tethering protein that creates contact site between the endoplasmic reticulum and late endosomes- localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB; Belongs to the STARD3 family | 0.588 |
| C17orf53 | ZBTB40 | ENSP00000313500 | ENSP00000384527 | Uncharacterized protein C17orf53; Chromosome 17 open reading frame 53 | Zinc finger and BTB domain-containing protein 40; May be involved in transcriptional regulation; BTB domain containing | 0.650 |
| DCDC1 | C17orf53 | ENSP00000385936 | ENSP00000313500 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Uncharacterized protein C17orf53; Chromosome 17 open reading frame 53 | 0.588 |
| DCDC1 | DCDC2 | ENSP00000385936 | ENSP00000367715 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway. May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length; Deafness associated genes | 0.656 |
| DCDC1 | DCDC2B | ENSP00000385936 | ENSP00000386870 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Doublecortin domain containing 2B | 0.806 |
| DCDC1 | DCX | ENSP00000385936 | ENSP00000337697 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Neuronal migration protein doublecortin; Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration; Dou [...] | 0.662 |
| DCDC1 | DNAJC24 | ENSP00000385936 | ENSP00000417548 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | DnaJ homolog subfamily C member 24; Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta); Belongs to the DPH4 family | 0.759 |
| DCDC1 | ELP4 | ENSP00000385936 | ENSP00000379267 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Elongator complex protein 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | 0.756 |
| DCDC1 | IMMP1L | ENSP00000385936 | ENSP00000278200 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.754 |
| DCDC1 | MPPED2 | ENSP00000385936 | ENSP00000350833 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Metallophosphoesterase MPPED2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity); Belongs to the UPF0046 family | 0.757 |
| DCDC1 | STARD3NL | ENSP00000385936 | ENSP00000009041 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | STARD3 N-terminal-like protein; Tethering protein that creates contact site between the endoplasmic reticulum and late endosomes- localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB; Belongs to the STARD3 family | 0.669 |
| DCDC1 | ZBTB40 | ENSP00000385936 | ENSP00000384527 | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | Zinc finger and BTB domain-containing protein 40; May be involved in transcriptional regulation; BTB domain containing | 0.654 |
| DCDC2 | DCDC1 | ENSP00000367715 | ENSP00000385936 | Doublecortin domain-containing protein 2; Protein that plays a role in the inhibition of canonical Wnt signaling pathway. May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length; Deafness associated genes | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | 0.656 |
| DCDC2B | DCDC1 | ENSP00000386870 | ENSP00000385936 | Doublecortin domain containing 2B | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | 0.806 |
| DCX | DCDC1 | ENSP00000337697 | ENSP00000385936 | Neuronal migration protein doublecortin; Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration; Dou [...] | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | 0.662 |
| DNAJC24 | DCDC1 | ENSP00000417548 | ENSP00000385936 | DnaJ homolog subfamily C member 24; Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta); Belongs to the DPH4 family | Doublecortin domain-containing protein 5; Doublecortin domain containing 1 | 0.759 |
| DNAJC24 | ELP4 | ENSP00000417548 | ENSP00000379267 | DnaJ homolog subfamily C member 24; Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta); Belongs to the DPH4 family | Elongator complex protein 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | 0.802 |
| DNAJC24 | IMMP1L | ENSP00000417548 | ENSP00000278200 | DnaJ homolog subfamily C member 24; Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta); Belongs to the DPH4 family | Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.785 |
| DNAJC24 | MPPED2 | ENSP00000417548 | ENSP00000350833 | DnaJ homolog subfamily C member 24; Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta); Belongs to the DPH4 family | Metallophosphoesterase MPPED2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity); Belongs to the UPF0046 family | 0.764 |
