FAM26D protein (human) - STRING database

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FAM26D

Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel (171 aa)

Predicted Functional Partners:

CWC25

0.841

KIAA0226L

0.841

ACOT11

0.841

C1orf109

0.841

SLCO1A2

0.841

LIX1

0.841

FBXO47

0.838

RDH13

0.837

PGM2

0.837

MOCS3

0.821

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT11	C1orf109	ENSP00000360366	ENSP00000350704	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	0.841
ACOT11	CWC25	ENSP00000360366	ENSP00000478070	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	CWC25 spliceosome associated protein homolog; Spliceosomal Bact complex	0.841
ACOT11	FAM26D	ENSP00000360366	ENSP00000385836	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel	0.841
ACOT11	FBXO47	ENSP00000360366	ENSP00000367319	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other	0.648
ACOT11	KIAA0226L	ENSP00000360366	ENSP00000396935	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Protein RUBCNL-like; May act as a tumor suppressor	0.841
ACOT11	LIX1	ENSP00000360366	ENSP00000274382	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family	0.841
ACOT11	MOCS3	ENSP00000360366	ENSP00000244051	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide t [...]	0.838
ACOT11	PGM2	ENSP00000360366	ENSP00000371393	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Phosphoglucomutase-2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity; Belongs to the phosphohexose mutase family	0.844
ACOT11	RDH13	ENSP00000360366	ENSP00000391121	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Retinol dehydrogenase 13; Does not exhibit retinol dehydrogenase (RDH) activity in vitro; Short chain dehydrogenase/reductase superfamily	0.828
ACOT11	SLCO1A2	ENSP00000360366	ENSP00000305974	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	Solute carrier organic anion transporter family member 1A2; Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin; Solute carriers	0.893
C1orf109	ACOT11	ENSP00000350704	ENSP00000360366	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates	0.841
C1orf109	CWC25	ENSP00000350704	ENSP00000478070	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	CWC25 spliceosome associated protein homolog; Spliceosomal Bact complex	0.841
C1orf109	FAM26D	ENSP00000350704	ENSP00000385836	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel	0.841
C1orf109	FBXO47	ENSP00000350704	ENSP00000367319	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other	0.836
C1orf109	KIAA0226L	ENSP00000350704	ENSP00000396935	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Protein RUBCNL-like; May act as a tumor suppressor	0.841
C1orf109	LIX1	ENSP00000350704	ENSP00000274382	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family	0.841
C1orf109	MOCS3	ENSP00000350704	ENSP00000244051	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide t [...]	0.839
C1orf109	PGM2	ENSP00000350704	ENSP00000371393	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Phosphoglucomutase-2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity; Belongs to the phosphohexose mutase family	0.841
C1orf109	RDH13	ENSP00000350704	ENSP00000391121	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Retinol dehydrogenase 13; Does not exhibit retinol dehydrogenase (RDH) activity in vitro; Short chain dehydrogenase/reductase superfamily	0.841
C1orf109	SLCO1A2	ENSP00000350704	ENSP00000305974	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Solute carrier organic anion transporter family member 1A2; Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin; Solute carriers	0.841

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