• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF727P ZNF727P USP17L1P USP17L1P PITPNA PITPNA PRSS46 PRSS46 ZNF735P ZNF735P PITPNC1 PITPNC1 SEC14L6 SEC14L6 PITPNM3 PITPNM3 PITPNB PITPNB PITPNM2 PITPNM2 PITPNM1 PITPNM1
"SEC14L6" - Putative SEC14-like protein 6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
SEC14L6Putative SEC14-like protein 6; SEC14 like lipid binding 6 (397 aa)    
Predicted Functional Partners:
PITPNB
Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins (272 aa)
     
 
  0.705
PITPNA
Phosphatidylinositol transfer protein alpha isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins (270 aa)
     
 
  0.705
PITPNM2
Membrane-associated phosphatidylinositol transfer protein 2; Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions (1349 aa)
     
 
  0.627
PITPNM1
Membrane-associated phosphatidylinositol transfer protein 1; Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golg [...] (1244 aa)
     
 
  0.607
PITPNC1
Cytoplasmic phosphatidylinositol transfer protein 1; Phosphatidylinositol transfer proteins mediate the monomeric transport of lipids by shielding a lipid from the aqueous environment and binding the lipid in a hydrophobic cavity. Able to transfer phosphatidylinositol in vitro (332 aa)
     
 
  0.605
PITPNM3
Membrane-associated phosphatidylinositol transfer protein 3; Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions; Atypical chemokine receptors (974 aa)
     
 
  0.605
ZNF735P
Zinc finger protein 735, pseudogene (568 aa)
     
 
  0.556
PRSS46
Protease, serine, 46; Belongs to the peptidase S1 family (174 aa)
           
  0.527
ZNF727P
Putative zinc finger protein 727; May be involved in transcriptional regulation (499 aa)
     
 
  0.500
USP17L1P
Ubiquitin carboxyl-terminal hydrolase 17-like protein 1; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
     
   
  0.446
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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