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  • 11.0 [archived version]
STRINGSTRING
CHAC2 CHAC2 ZNF48 ZNF48 FAM188A FAM188A UBL7 UBL7 CCDC97 CCDC97 RWDD1 RWDD1 ZNF428 ZNF428 GAGE10 GAGE10 CRYZL1 CRYZL1 SAMHD1 SAMHD1 PPP1R3F PPP1R3F
"GAGE10" - G antigen 10 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAGE10G antigen 10; Belongs to the GAGE family (116 aa)    
Predicted Functional Partners:
SAMHD1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling. Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction; Sterile alpha motif domain containing (626 aa)
            
  0.641
CRYZL1
Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily (349 aa)
            
  0.640
PPP1R3F
Protein phosphatase 1 regulatory subunit 3F; Glycogen-targeting subunit for protein phosphatase 1 (PP1) (799 aa)
            
  0.633
ZNF428
Zinc finger protein 428; Zinc fingers C2H2-type (188 aa)
            
  0.575
CCDC97
Coiled-coil domain containing 97 (343 aa)
            
  0.571
UBL7
Ubiquitin-like protein 7; Ubiquitin like 7 (380 aa)
            
  0.557
RWDD1
RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family (243 aa)
            
  0.548
CHAC2
Glutathione-specific gamma-glutamylcyclotransferase 2; Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides (184 aa)
            
  0.475
FAM188A
Ubiquitin carboxyl-terminal hydrolase MINDY-3; Hydrolase that can remove ’Lys-48’-linked conjugated ubiquitin from proteins (445 aa)
            
  0.474
ZNF48
Zinc finger protein 48; May be involved in transcriptional regulation; Zinc fingers C2H2-type (618 aa)
            
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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