• Version:
  • 11.0 [archived version]
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GFAP GFAP FBXL7 FBXL7 LRRC56 LRRC56 LRRC46 LRRC46 SHROOM3 SHROOM3 ELFN2 ELFN2 SOWAHB SOWAHB C2CD4C C2CD4C ZNF606 ZNF606 ZBTB39 ZBTB39 ZC3H3 ZC3H3
"ELFN2" - Protein phosphatase 1 regulatory subunit 29 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ELFN2Protein phosphatase 1 regulatory subunit 29; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Fibronectin type III domain containing (820 aa)    
Predicted Functional Partners:
SOWAHB
Ankyrin repeat domain-containing protein SOWAHB; Sosondowah ankyrin repeat domain family member B; Belongs to the SOWAH family (793 aa)
     
   
  0.700
SHROOM3
Protein Shroom3; Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity); Belongs to the shroom family (1996 aa)
           
  0.641
C2CD4C
C2 calcium-dependent domain-containing protein 4C; C2 calcium dependent domain containing 4C; Belongs to the C2CD4 family (421 aa)
     
   
  0.623
LRRC46
Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46 (321 aa)
           
  0.587
GFAP
Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells (438 aa)
     
        0.574
LRRC56
Leucine-rich repeat-containing protein 56; Leucine rich repeat containing 56 (542 aa)
           
  0.574
FBXL7
F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest; F-box and leucine rich repeat proteins (491 aa)
           
  0.560
ZNF606
Zinc finger protein 606; May act as a transcriptional repressor; Zinc fingers C2H2-type (792 aa)
           
  0.559
ZC3H3
Zinc finger CCCH domain-containing protein 3; Required for the export of polyadenylated mRNAs from the nucleus. Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double- stranded DNA in vitro. Involved in RNA cleavage (By similarity); Zinc fingers CCCH-type (948 aa)
           
  0.554
ZBTB39
Zinc finger and BTB domain-containing protein 39; May be involved in transcriptional regulation; BTB domain containing (712 aa)
           
  0.550
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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