node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APPL1 | ZNF155 | ENSP00000288266 | ENSP00000385163 | DCC-interacting protein 13-alpha; Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway; BAR-PH domain containing | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.418 |
B9D1 | ZNF155 | ENSP00000261499 | ENSP00000385163 | B9 domain-containing protein 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the B9D family | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.418 |
HTN3 | ZNF155 | ENSP00000432561 | ENSP00000385163 | Histatin-3; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.629 |
NGRN | ZNF155 | ENSP00000368389 | ENSP00000385163 | Neugrin; May be involved in neuronal differentiation | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.493 |
TARBP1 | TRUB1 | ENSP00000040877 | ENSP00000298746 | Probable methyltransferase TARBP1; Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA; Armadillo-like helical domain containing | Probable tRNA pseudouridine synthase 1; May be responsible for synthesis of pseudouridine from uracil in transfer RNAs | 0.799 |
TARBP1 | ZNF155 | ENSP00000040877 | ENSP00000385163 | Probable methyltransferase TARBP1; Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA; Armadillo-like helical domain containing | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.474 |
TRIM28 | ZNF155 | ENSP00000253024 | ENSP00000385163 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.904 |
TRUB1 | TARBP1 | ENSP00000298746 | ENSP00000040877 | Probable tRNA pseudouridine synthase 1; May be responsible for synthesis of pseudouridine from uracil in transfer RNAs | Probable methyltransferase TARBP1; Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA; Armadillo-like helical domain containing | 0.799 |
TRUB1 | ZNF155 | ENSP00000298746 | ENSP00000385163 | Probable tRNA pseudouridine synthase 1; May be responsible for synthesis of pseudouridine from uracil in transfer RNAs | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.511 |
ZNF155 | APPL1 | ENSP00000385163 | ENSP00000288266 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | DCC-interacting protein 13-alpha; Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway; BAR-PH domain containing | 0.418 |
ZNF155 | B9D1 | ENSP00000385163 | ENSP00000261499 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | B9 domain-containing protein 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the B9D family | 0.418 |
ZNF155 | HTN3 | ENSP00000385163 | ENSP00000432561 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Histatin-3; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9 | 0.629 |
ZNF155 | NGRN | ENSP00000385163 | ENSP00000368389 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Neugrin; May be involved in neuronal differentiation | 0.493 |
ZNF155 | TARBP1 | ENSP00000385163 | ENSP00000040877 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Probable methyltransferase TARBP1; Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA; Armadillo-like helical domain containing | 0.474 |
ZNF155 | TRIM28 | ENSP00000385163 | ENSP00000253024 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.904 |
ZNF155 | TRUB1 | ENSP00000385163 | ENSP00000298746 | Zinc finger protein 155; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | Probable tRNA pseudouridine synthase 1; May be responsible for synthesis of pseudouridine from uracil in transfer RNAs | 0.511 |