node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADTRP | SULT6B1 | ENSP00000229583 | ENSP00000384950 | Androgen-dependent TFPI-regulating protein; Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro) | Sulfotransferase 6B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity); Sulfotransferases, cytosolic | 0.404 |
CCDC94 | RALGPS2 | ENSP00000262962 | ENSP00000356607 | Coiled-coil domain containing 94 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | 0.479 |
CCDC94 | SULT6B1 | ENSP00000262962 | ENSP00000384950 | Coiled-coil domain containing 94 | Sulfotransferase 6B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity); Sulfotransferases, cytosolic | 0.793 |
CCDC94 | ZDHHC23 | ENSP00000262962 | ENSP00000330485 | Coiled-coil domain containing 94 | Palmitoyltransferase ZDHHC23; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane; Zinc fingers DHHC-type | 0.762 |
FRMD1 | KIF25 | ENSP00000283309 | ENSP00000388878 | FERM domain containing 1 | Kinesin-like protein KIF25; Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase. Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis. May also act as a negative regulator of amino acid starvation-induced autophagy; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | 0.713 |
FRMD1 | MAATS1 | ENSP00000283309 | ENSP00000273390 | FERM domain containing 1 | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | 0.676 |
FRMD1 | SULT6B1 | ENSP00000283309 | ENSP00000384950 | FERM domain containing 1 | Sulfotransferase 6B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity); Sulfotransferases, cytosolic | 0.440 |
KIF25 | FRMD1 | ENSP00000388878 | ENSP00000283309 | Kinesin-like protein KIF25; Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase. Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis. May also act as a negative regulator of amino acid starvation-induced autophagy; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | FERM domain containing 1 | 0.713 |
KIF25 | MAATS1 | ENSP00000388878 | ENSP00000273390 | Kinesin-like protein KIF25; Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase. Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis. May also act as a negative regulator of amino acid starvation-induced autophagy; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | 0.684 |
KIF25 | SULT6B1 | ENSP00000388878 | ENSP00000384950 | Kinesin-like protein KIF25; Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase. Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis. May also act as a negative regulator of amino acid starvation-induced autophagy; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | Sulfotransferase 6B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity); Sulfotransferases, cytosolic | 0.453 |
MAATS1 | FRMD1 | ENSP00000273390 | ENSP00000283309 | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | FERM domain containing 1 | 0.676 |
MAATS1 | KIF25 | ENSP00000273390 | ENSP00000388878 | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Kinesin-like protein KIF25; Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase. Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis. May also act as a negative regulator of amino acid starvation-induced autophagy; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | 0.684 |
MAATS1 | SULT6B1 | ENSP00000273390 | ENSP00000384950 | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Sulfotransferase 6B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity); Sulfotransferases, cytosolic | 0.472 |
RALGPS2 | CCDC94 | ENSP00000356607 | ENSP00000262962 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | Coiled-coil domain containing 94 | 0.479 |
RALGPS2 | SPTBN5 | ENSP00000356607 | ENSP00000317790 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | Spectrin beta, non-erythrocytic 5; Spectrins | 0.417 |
RALGPS2 | SULT6B1 | ENSP00000356607 | ENSP00000384950 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | Sulfotransferase 6B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity); Sulfotransferases, cytosolic | 0.502 |
RALGPS2 | ZDHHC23 | ENSP00000356607 | ENSP00000330485 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | Palmitoyltransferase ZDHHC23; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane; Zinc fingers DHHC-type | 0.554 |
SPTBN5 | RALGPS2 | ENSP00000317790 | ENSP00000356607 | Spectrin beta, non-erythrocytic 5; Spectrins | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | 0.417 |
SPTBN5 | SULT6B1 | ENSP00000317790 | ENSP00000384950 | Spectrin beta, non-erythrocytic 5; Spectrins | Sulfotransferase 6B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine. Involved in the metabolism of thyroxine (By similarity); Sulfotransferases, cytosolic | 0.738 |
SPTBN5 | ZDHHC23 | ENSP00000317790 | ENSP00000330485 | Spectrin beta, non-erythrocytic 5; Spectrins | Palmitoyltransferase ZDHHC23; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane; Zinc fingers DHHC-type | 0.735 |