node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCC2 | SVEP1 | ENSP00000307939 | ENSP00000384917 | GRIP and coiled-coil domain-containing protein 2; Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2 | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process; Sushi domain containing | 0.678 |
HDHD3 | KIF12 | ENSP00000238379 | ENSP00000363232 | Haloacid dehalogenase like hydrolase domain containing 3 | Kinesin-like protein KIF12; Kinesin family member 12; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | 0.698 |
HDHD3 | SFXN3 | ENSP00000238379 | ENSP00000224807 | Haloacid dehalogenase like hydrolase domain containing 3 | Sideroflexin-3; Potential iron transporter; Sideroflexins | 0.446 |
HDHD3 | SVEP1 | ENSP00000238379 | ENSP00000384917 | Haloacid dehalogenase like hydrolase domain containing 3 | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process; Sushi domain containing | 0.582 |
HSPA14 | SFXN1 | ENSP00000367623 | ENSP00000316905 | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | Sideroflexin-1; Might be involved in the transport of a component required for iron utilization into or out of the mitochondria; Sideroflexins | 0.526 |
HSPA14 | SFXN2 | ENSP00000367623 | ENSP00000358909 | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | Sideroflexin-2; Potential iron transporter; Sideroflexins | 0.539 |
HSPA14 | SFXN3 | ENSP00000367623 | ENSP00000224807 | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | Sideroflexin-3; Potential iron transporter; Sideroflexins | 0.575 |
HSPA14 | SFXN5 | ENSP00000367623 | ENSP00000272433 | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | Sideroflexin-5; Transports citrate. Potential iron transporter (By similarity); Sideroflexins | 0.539 |
HSPA14 | SNRNP200 | ENSP00000367623 | ENSP00000317123 | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | U5 small nuclear ribonucleoprotein 200 kDa helicase; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome | 0.588 |
HSPA14 | SVEP1 | ENSP00000367623 | ENSP00000384917 | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process; Sushi domain containing | 0.610 |
KIF12 | HDHD3 | ENSP00000363232 | ENSP00000238379 | Kinesin-like protein KIF12; Kinesin family member 12; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | Haloacid dehalogenase like hydrolase domain containing 3 | 0.698 |
KIF12 | SVEP1 | ENSP00000363232 | ENSP00000384917 | Kinesin-like protein KIF12; Kinesin family member 12; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process; Sushi domain containing | 0.589 |
SFXN1 | HSPA14 | ENSP00000316905 | ENSP00000367623 | Sideroflexin-1; Might be involved in the transport of a component required for iron utilization into or out of the mitochondria; Sideroflexins | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | 0.526 |
SFXN1 | SNRNP200 | ENSP00000316905 | ENSP00000317123 | Sideroflexin-1; Might be involved in the transport of a component required for iron utilization into or out of the mitochondria; Sideroflexins | U5 small nuclear ribonucleoprotein 200 kDa helicase; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome | 0.622 |
SFXN1 | SVEP1 | ENSP00000316905 | ENSP00000384917 | Sideroflexin-1; Might be involved in the transport of a component required for iron utilization into or out of the mitochondria; Sideroflexins | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process; Sushi domain containing | 0.626 |
SFXN2 | HSPA14 | ENSP00000358909 | ENSP00000367623 | Sideroflexin-2; Potential iron transporter; Sideroflexins | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | 0.539 |
SFXN2 | SNRNP200 | ENSP00000358909 | ENSP00000317123 | Sideroflexin-2; Potential iron transporter; Sideroflexins | U5 small nuclear ribonucleoprotein 200 kDa helicase; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome | 0.626 |
SFXN2 | SVEP1 | ENSP00000358909 | ENSP00000384917 | Sideroflexin-2; Potential iron transporter; Sideroflexins | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process; Sushi domain containing | 0.626 |
SFXN3 | HDHD3 | ENSP00000224807 | ENSP00000238379 | Sideroflexin-3; Potential iron transporter; Sideroflexins | Haloacid dehalogenase like hydrolase domain containing 3 | 0.446 |
SFXN3 | HSPA14 | ENSP00000224807 | ENSP00000367623 | Sideroflexin-3; Potential iron transporter; Sideroflexins | Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity; Belongs to the heat shock protein 70 family | 0.575 |