| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABTB1 | ABTB2 | ENSP00000232744 | ENSP00000410157 | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | 0.613 |
| ABTB1 | BTBD3 | ENSP00000232744 | ENSP00000384545 | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | 0.669 |
| ABTB1 | BTBD6 | ENSP00000232744 | ENSP00000376337 | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | BTB/POZ domain-containing protein 6; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity); BTB domain containing | 0.702 |
| ABTB1 | BTBD9 | ENSP00000232744 | ENSP00000418751 | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | BTB/POZ domain-containing protein 9; BTB domain containing 9 | 0.540 |
| ABTB1 | CUL1 | ENSP00000232744 | ENSP00000326804 | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the [...] | 0.865 |
| ABTB1 | FBXW4 | ENSP00000232744 | ENSP00000359149 | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | F-box/WD repeat-containing protein 4; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling; F-box and WD repeat domain containing | 0.540 |
| ABTB2 | ABTB1 | ENSP00000410157 | ENSP00000232744 | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | 0.613 |
| ABTB2 | BTBD3 | ENSP00000410157 | ENSP00000384545 | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | 0.587 |
| ABTB2 | BTBD6 | ENSP00000410157 | ENSP00000376337 | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | BTB/POZ domain-containing protein 6; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity); BTB domain containing | 0.725 |
| ABTB2 | BTBD9 | ENSP00000410157 | ENSP00000418751 | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | BTB/POZ domain-containing protein 9; BTB domain containing 9 | 0.540 |
| ABTB2 | CUL1 | ENSP00000410157 | ENSP00000326804 | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the [...] | 0.550 |
| ABTB2 | FBXW4 | ENSP00000410157 | ENSP00000359149 | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | F-box/WD repeat-containing protein 4; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling; F-box and WD repeat domain containing | 0.549 |
| ARHGEF39 | BTBD3 | ENSP00000367638 | ENSP00000384545 | Rho guanine nucleotide exchange factor 39; Promotes cell proliferation | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | 0.580 |
| ARHGEF39 | CCDC90B | ENSP00000367638 | ENSP00000434724 | Rho guanine nucleotide exchange factor 39; Promotes cell proliferation | Coiled-coil domain-containing protein 90B, mitochondrial; Coiled-coil domain containing 90B | 0.586 |
| BTBD3 | ABTB1 | ENSP00000384545 | ENSP00000232744 | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes; Ankyrin repeat domain containing | 0.669 |
| BTBD3 | ABTB2 | ENSP00000384545 | ENSP00000410157 | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | Ankyrin repeat and BTB/POZ domain-containing protein 2; May be involved in the initiation of hepatocyte growth; Ankyrin repeat domain containing | 0.587 |
| BTBD3 | ARHGEF39 | ENSP00000384545 | ENSP00000367638 | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | Rho guanine nucleotide exchange factor 39; Promotes cell proliferation | 0.580 |
| BTBD3 | BTBD6 | ENSP00000384545 | ENSP00000376337 | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | BTB/POZ domain-containing protein 6; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity); BTB domain containing | 0.907 |
| BTBD3 | BTBD9 | ENSP00000384545 | ENSP00000418751 | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | BTB/POZ domain-containing protein 9; BTB domain containing 9 | 0.613 |
| BTBD3 | CCDC90B | ENSP00000384545 | ENSP00000434724 | BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing | Coiled-coil domain-containing protein 90B, mitochondrial; Coiled-coil domain containing 90B | 0.579 |
