| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CFAP69 | FAM133B | ENSP00000373948 | ENSP00000398401 | Cilia- and flagella-associated protein 69; Armadillo-like helical domain containing | Protein FAM133B; Family with sequence similarity 133 member B | 0.475 |
| CFAP69 | STEAP1B | ENSP00000373948 | ENSP00000384370 | Cilia- and flagella-associated protein 69; Armadillo-like helical domain containing | STEAP family member 1B; Belongs to the STEAP family | 0.548 |
| CPSF4 | STEAP1 | ENSP00000292476 | ENSP00000297205 | Cleavage and polyadenylation specificity factor subunit 4; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U) | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | 0.482 |
| CPSF4 | STEAP1B | ENSP00000292476 | ENSP00000384370 | Cleavage and polyadenylation specificity factor subunit 4; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U) | STEAP family member 1B; Belongs to the STEAP family | 0.453 |
| DARS | MUC16 | ENSP00000264161 | ENSP00000381008 | Aspartate--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces; Mucins | 0.581 |
| DARS | STEAP1 | ENSP00000264161 | ENSP00000297205 | Aspartate--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | 0.613 |
| DARS | STEAP1B | ENSP00000264161 | ENSP00000384370 | Aspartate--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily | STEAP family member 1B; Belongs to the STEAP family | 0.505 |
| FAM133B | CFAP69 | ENSP00000398401 | ENSP00000373948 | Protein FAM133B; Family with sequence similarity 133 member B | Cilia- and flagella-associated protein 69; Armadillo-like helical domain containing | 0.475 |
| FAM133B | STEAP1B | ENSP00000398401 | ENSP00000384370 | Protein FAM133B; Family with sequence similarity 133 member B | STEAP family member 1B; Belongs to the STEAP family | 0.540 |
| GPR176 | STEAP1B | ENSP00000453076 | ENSP00000384370 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production | STEAP family member 1B; Belongs to the STEAP family | 0.492 |
| MUC16 | DARS | ENSP00000381008 | ENSP00000264161 | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces; Mucins | Aspartate--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily | 0.581 |
| MUC16 | STEAP1 | ENSP00000381008 | ENSP00000297205 | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces; Mucins | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | 0.534 |
| MUC16 | STEAP1B | ENSP00000381008 | ENSP00000384370 | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces; Mucins | STEAP family member 1B; Belongs to the STEAP family | 0.406 |
| PLCXD1 | STEAP1B | ENSP00000371073 | ENSP00000384370 | PI-PLC X domain-containing protein 1; Phosphatidylinositol specific phospholipase C X domain containing 1; Pseudoautosomal region 1 | STEAP family member 1B; Belongs to the STEAP family | 0.444 |
| SPSB1 | STEAP1B | ENSP00000330221 | ENSP00000384370 | SPRY domain-containing SOCS box protein 1; Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the SPSB family | STEAP family member 1B; Belongs to the STEAP family | 0.416 |
| STEAP1 | CPSF4 | ENSP00000297205 | ENSP00000292476 | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | Cleavage and polyadenylation specificity factor subunit 4; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U) | 0.482 |
| STEAP1 | DARS | ENSP00000297205 | ENSP00000264161 | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | Aspartate--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily | 0.613 |
| STEAP1 | MUC16 | ENSP00000297205 | ENSP00000381008 | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces; Mucins | 0.534 |
| STEAP1 | STEAP1B | ENSP00000297205 | ENSP00000384370 | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | STEAP family member 1B; Belongs to the STEAP family | 0.710 |
| STEAP1 | TRIAP1 | ENSP00000297205 | ENSP00000449795 | Metalloreductase STEAP1; Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity); Belongs to the STEAP family | TP53-regulated inhibitor of apoptosis 1; Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1-PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1-PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter acros [...] | 0.515 |
