node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FER1L6 | IMMP2L | ENSP00000428280 | ENSP00000384966 | Fer-1-like protein 6; Fer-1 like family member 6 | Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO; Belongs to the peptidase S26 family. IMP2 subfamily | 0.537 |
FER1L6 | MEIG1 | ENSP00000428280 | ENSP00000384334 | Fer-1-like protein 6; Fer-1 like family member 6 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | 0.584 |
IMMP2L | FER1L6 | ENSP00000384966 | ENSP00000428280 | Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO; Belongs to the peptidase S26 family. IMP2 subfamily | Fer-1-like protein 6; Fer-1 like family member 6 | 0.537 |
IMMP2L | MEIG1 | ENSP00000384966 | ENSP00000384334 | Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO; Belongs to the peptidase S26 family. IMP2 subfamily | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | 0.499 |
IQCG | MEIG1 | ENSP00000265239 | ENSP00000384334 | IQ domain-containing protein G; Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin- dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades (Probable). Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | 0.712 |
MEIG1 | FER1L6 | ENSP00000384334 | ENSP00000428280 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Fer-1-like protein 6; Fer-1 like family member 6 | 0.584 |
MEIG1 | IMMP2L | ENSP00000384334 | ENSP00000384966 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO; Belongs to the peptidase S26 family. IMP2 subfamily | 0.499 |
MEIG1 | IQCG | ENSP00000384334 | ENSP00000265239 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | IQ domain-containing protein G; Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin- dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades (Probable). Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility | 0.712 |
MEIG1 | MORN3 | ENSP00000384334 | ENSP00000347486 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | MORN repeat containing 3 | 0.633 |
MEIG1 | PACRG | ENSP00000384334 | ENSP00000337946 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease; Armadillo-like helical domain containing | 0.825 |
MEIG1 | RSPH1 | ENSP00000384334 | ENSP00000291536 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes | 0.510 |
MEIG1 | SPAG16 | ENSP00000384334 | ENSP00000332592 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Sperm-associated antigen 16 protein; Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity); WD repeat domain containing | 0.992 |
MEIG1 | SPAG6 | ENSP00000384334 | ENSP00000365811 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Sperm-associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility; Armadillo repeat containing | 0.935 |
MEIG1 | SPATA4 | ENSP00000384334 | ENSP00000280191 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Spermatogenesis-associated protein 4; Spermatogenesis associated 4 | 0.690 |
MEIG1 | TEKT2 | ENSP00000384334 | ENSP00000207457 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Tektins | 0.531 |
MORN3 | MEIG1 | ENSP00000347486 | ENSP00000384334 | MORN repeat containing 3 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | 0.633 |
MORN3 | PACRG | ENSP00000347486 | ENSP00000337946 | MORN repeat containing 3 | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease; Armadillo-like helical domain containing | 0.518 |
MORN3 | RSPH1 | ENSP00000347486 | ENSP00000291536 | MORN repeat containing 3 | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes | 0.510 |
MORN3 | SPAG16 | ENSP00000347486 | ENSP00000332592 | MORN repeat containing 3 | Sperm-associated antigen 16 protein; Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity); WD repeat domain containing | 0.416 |
PACRG | MEIG1 | ENSP00000337946 | ENSP00000384334 | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease; Armadillo-like helical domain containing | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis | 0.825 |