node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BNIP1 | COG4 | ENSP00000231668 | ENSP00000315775 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1; Belongs to the COG4 family | 0.588 |
BNIP1 | NBAS | ENSP00000231668 | ENSP00000281513 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Neuroblastoma-amplified sequence; Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER | 0.952 |
BNIP1 | RINT1 | ENSP00000231668 | ENSP00000257700 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | RAD50-interacting protein 1; Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control; Belongs to the RINT1 family | 0.992 |
BNIP1 | SCFD2 | ENSP00000231668 | ENSP00000384182 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Sec1 family domain-containing protein 2; May be involved in protein transport | 0.917 |
BNIP1 | SEC22B | ENSP00000231668 | ENSP00000463393 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER; Belongs to the synaptobrevin family | 0.986 |
BNIP1 | STX18 | ENSP00000231668 | ENSP00000305810 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER; Syntaxins | 0.998 |
BNIP1 | USE1 | ENSP00000231668 | ENSP00000263897 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER; SNAREs | 0.993 |
BNIP1 | VAMP4 | ENSP00000231668 | ENSP00000236192 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule; Vesicle associated membrane proteins | 0.823 |
BNIP1 | ZW10 | ENSP00000231668 | ENSP00000200135 | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assemb [...] | 0.976 |
C19orf25 | RINT1 | ENSP00000397394 | ENSP00000257700 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | RAD50-interacting protein 1; Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control; Belongs to the RINT1 family | 0.969 |
C19orf25 | SCFD2 | ENSP00000397394 | ENSP00000384182 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | Sec1 family domain-containing protein 2; May be involved in protein transport | 0.865 |
C19orf25 | SEC22B | ENSP00000397394 | ENSP00000463393 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER; Belongs to the synaptobrevin family | 0.646 |
C19orf25 | USE1 | ENSP00000397394 | ENSP00000263897 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER; SNAREs | 0.727 |
C19orf25 | ZW10 | ENSP00000397394 | ENSP00000200135 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assemb [...] | 0.503 |
COG4 | BNIP1 | ENSP00000315775 | ENSP00000231668 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1; Belongs to the COG4 family | BCL2/adenovirus E1B 19kDa interacting protein 1; BCL2 homology region 3 only | 0.588 |
COG4 | RINT1 | ENSP00000315775 | ENSP00000257700 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1; Belongs to the COG4 family | RAD50-interacting protein 1; Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control; Belongs to the RINT1 family | 0.806 |
COG4 | SCFD2 | ENSP00000315775 | ENSP00000384182 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1; Belongs to the COG4 family | Sec1 family domain-containing protein 2; May be involved in protein transport | 0.712 |
COG4 | STX18 | ENSP00000315775 | ENSP00000305810 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1; Belongs to the COG4 family | Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER; Syntaxins | 0.704 |
COG4 | VAMP4 | ENSP00000315775 | ENSP00000236192 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1; Belongs to the COG4 family | Vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule; Vesicle associated membrane proteins | 0.950 |
COG4 | ZW10 | ENSP00000315775 | ENSP00000200135 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1; Belongs to the COG4 family | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assemb [...] | 0.679 |