• Version:
  • 11.0 [archived version]
STRINGSTRING
SULT4A1 SULT4A1 RUNDC3A RUNDC3A SEPT14 SEPT14 ZNF713 ZNF713 LANCL2 LANCL2 SH3RF2 SH3RF2 VSTM2A VSTM2A VOPP1 VOPP1 PGBD5 PGBD5 LONRF2 LONRF2 PNMAL1 PNMAL1
"VSTM2A" - V-set and transmembrane domain-containing protein 2A in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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VSTM2AV-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing (240 aa)    
Predicted Functional Partners:
ZNF713
Zinc finger protein 713; May be involved in transcriptional regulation; Zinc fingers C2H2-type (430 aa)
           
  0.645
SULT4A1
Sulfotransferase 4A1; Atypical sulfotransferase family member with very low affinity for 3’-phospho-5’-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS; Sulfotransferases, cytosolic (284 aa)
     
   
  0.624
LONRF2
LON peptidase N-terminal domain and ring finger 2 (754 aa)
     
   
  0.623
PNMAL1
Paraneoplastic antigen-like protein 8A; Paraneoplastic Ma antigen family-like 1 (439 aa)
     
   
  0.621
LANCL2
LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (450 aa)
     
   
  0.617
SEPT14
Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Septins (432 aa)
           
  0.605
PGBD5
PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes (455 aa)
     
   
  0.588
VOPP1
Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family (172 aa)
     
   
  0.579
SH3RF2
Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family (729 aa)
           
  0.569
RUNDC3A
RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells; Belongs to the RUNDC3 family (446 aa)
     
   
  0.553
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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