node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LANCL2 | SEPT14 | ENSP00000254770 | ENSP00000373627 | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes | Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Septins | 0.581 |
LANCL2 | VOPP1 | ENSP00000254770 | ENSP00000285279 | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes | Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family | 0.728 |
LANCL2 | VSTM2A | ENSP00000254770 | ENSP00000384103 | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes | V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing | 0.617 |
LANCL2 | ZNF713 | ENSP00000254770 | ENSP00000416662 | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes | Zinc finger protein 713; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.604 |
LONRF2 | PGBD5 | ENSP00000377086 | ENSP00000431404 | LON peptidase N-terminal domain and ring finger 2 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes | 0.606 |
LONRF2 | PNMAL1 | ENSP00000377086 | ENSP00000318131 | LON peptidase N-terminal domain and ring finger 2 | Paraneoplastic antigen-like protein 8A; Paraneoplastic Ma antigen family-like 1 | 0.637 |
LONRF2 | VSTM2A | ENSP00000377086 | ENSP00000384103 | LON peptidase N-terminal domain and ring finger 2 | V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing | 0.623 |
PGBD5 | LONRF2 | ENSP00000431404 | ENSP00000377086 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes | LON peptidase N-terminal domain and ring finger 2 | 0.606 |
PGBD5 | PNMAL1 | ENSP00000431404 | ENSP00000318131 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes | Paraneoplastic antigen-like protein 8A; Paraneoplastic Ma antigen family-like 1 | 0.650 |
PGBD5 | VSTM2A | ENSP00000431404 | ENSP00000384103 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes | V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing | 0.588 |
PNMAL1 | LONRF2 | ENSP00000318131 | ENSP00000377086 | Paraneoplastic antigen-like protein 8A; Paraneoplastic Ma antigen family-like 1 | LON peptidase N-terminal domain and ring finger 2 | 0.637 |
PNMAL1 | PGBD5 | ENSP00000318131 | ENSP00000431404 | Paraneoplastic antigen-like protein 8A; Paraneoplastic Ma antigen family-like 1 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes | 0.650 |
PNMAL1 | VSTM2A | ENSP00000318131 | ENSP00000384103 | Paraneoplastic antigen-like protein 8A; Paraneoplastic Ma antigen family-like 1 | V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing | 0.621 |
RUNDC3A | SULT4A1 | ENSP00000410862 | ENSP00000332565 | RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells; Belongs to the RUNDC3 family | Sulfotransferase 4A1; Atypical sulfotransferase family member with very low affinity for 3’-phospho-5’-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS; Sulfotransferases, cytosolic | 0.403 |
RUNDC3A | VSTM2A | ENSP00000410862 | ENSP00000384103 | RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells; Belongs to the RUNDC3 family | V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing | 0.553 |
SEPT14 | LANCL2 | ENSP00000373627 | ENSP00000254770 | Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Septins | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes | 0.581 |
SEPT14 | VOPP1 | ENSP00000373627 | ENSP00000285279 | Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Septins | Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family | 0.491 |
SEPT14 | VSTM2A | ENSP00000373627 | ENSP00000384103 | Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Septins | V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing | 0.605 |
SEPT14 | ZNF713 | ENSP00000373627 | ENSP00000416662 | Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Septins | Zinc finger protein 713; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.634 |
SH3RF2 | VSTM2A | ENSP00000424497 | ENSP00000384103 | Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family | V-set and transmembrane domain-containing protein 2A; Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway; V-set domain containing | 0.569 |