ZNF681 protein (human) - STRING database

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ZNF681

Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type (645 aa)

Predicted Functional Partners:

TRIM28

0.904

OR52N4

0.646

TIGD7

0.627

TIGD6

0.582

NKAPL

0.559

PHKG2

0.475

ERV3-1

0.459

ABCC12

0.459

ABCA13

0.442

SRCAP

0.438

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA13	TIGD7	ENSP00000411096	ENSP00000380071	ATP binding cassette subfamily A member 13	Tigger transposable element-derived protein 7; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family	0.516
ABCA13	ZNF681	ENSP00000411096	ENSP00000384000	ATP binding cassette subfamily A member 13	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.442
ABCC12	ZNF681	ENSP00000311030	ENSP00000384000	Multidrug resistance-associated protein 9; Probable transporter; ATP binding cassette subfamily C	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.459
ERV3-1	ZNF681	ENSP00000391594	ENSP00000384000	Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.459
NKAPL	ZNF681	ENSP00000345716	ENSP00000384000	NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.559
OR52N4	TIGD6	ENSP00000323224	ENSP00000296736	Olfactory receptor 52N4; Odorant receptor; Olfactory receptors, family 52	Tigger transposable element-derived protein 6; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes	0.506
OR52N4	TIGD7	ENSP00000323224	ENSP00000380071	Olfactory receptor 52N4; Odorant receptor; Olfactory receptors, family 52	Tigger transposable element-derived protein 7; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family	0.531
OR52N4	ZNF681	ENSP00000323224	ENSP00000384000	Olfactory receptor 52N4; Odorant receptor; Olfactory receptors, family 52	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.646
PHKG2	ZNF681	ENSP00000455607	ENSP00000384000	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.475
SRCAP	ZNF681	ENSP00000262518	ENSP00000384000	Helicase SRCAP; Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.438
TIGD6	OR52N4	ENSP00000296736	ENSP00000323224	Tigger transposable element-derived protein 6; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes	Olfactory receptor 52N4; Odorant receptor; Olfactory receptors, family 52	0.506
TIGD6	ZNF681	ENSP00000296736	ENSP00000384000	Tigger transposable element-derived protein 6; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.582
TIGD7	ABCA13	ENSP00000380071	ENSP00000411096	Tigger transposable element-derived protein 7; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family	ATP binding cassette subfamily A member 13	0.516
TIGD7	OR52N4	ENSP00000380071	ENSP00000323224	Tigger transposable element-derived protein 7; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family	Olfactory receptor 52N4; Odorant receptor; Olfactory receptors, family 52	0.531
TIGD7	ZNF681	ENSP00000380071	ENSP00000384000	Tigger transposable element-derived protein 7; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.627
TRIM28	ZNF681	ENSP00000253024	ENSP00000384000	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.904
ZNF681	ABCA13	ENSP00000384000	ENSP00000411096	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	ATP binding cassette subfamily A member 13	0.442
ZNF681	ABCC12	ENSP00000384000	ENSP00000311030	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Multidrug resistance-associated protein 9; Probable transporter; ATP binding cassette subfamily C	0.459
ZNF681	ERV3-1	ENSP00000384000	ENSP00000391594	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes	0.459
ZNF681	NKAPL	ENSP00000384000	ENSP00000345716	Zinc finger protein 681; May be involved in transcriptional regulation; Zinc fingers C2H2-type	NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis	0.559

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