| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BLCAP | EFCAB8 | ENSP00000397172 | ENSP00000383366 | Bladder cancer-associated protein; May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.445 |
| CSRP2 | EFCAB8 | ENSP00000310901 | ENSP00000383366 | Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system; LIM domain containing | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.446 |
| EFCAB8 | BLCAP | ENSP00000383366 | ENSP00000397172 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | Bladder cancer-associated protein; May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B | 0.445 |
| EFCAB8 | CSRP2 | ENSP00000383366 | ENSP00000310901 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system; LIM domain containing | 0.446 |
| EFCAB8 | ENSG00000272772 | ENSP00000383366 | ENSP00000430774 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | Uncharacterized protein; Belongs to the SKP1 family | 0.516 |
| EFCAB8 | GNRH2 | ENSP00000383366 | ENSP00000245983 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | Progonadoliberin-2; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family | 0.441 |
| EFCAB8 | IL36G | ENSP00000383366 | ENSP00000259205 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | Interleukin-36 gamma; Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinoc [...] | 0.414 |
| EFCAB8 | KCMF1 | ENSP00000383366 | ENSP00000386738 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | E3 ubiquitin-protein ligase KCMF1; Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination; Belongs to the KCMF1 family | 0.422 |
| EFCAB8 | SKP1 | ENSP00000383366 | ENSP00000231487 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] | 0.476 |
| EFCAB8 | SMIM1 | ENSP00000383366 | ENSP00000457386 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | Small integral membrane protein 1; Regulator of red blood cell formation; Belongs to the SMIM1 family | 0.497 |
| EFCAB8 | VSTM2L | ENSP00000383366 | ENSP00000362560 | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | V-set and transmembrane domain-containing protein 2-like protein; V-set and transmembrane domain containing 2 like | 0.642 |
| ENSG00000272772 | EFCAB8 | ENSP00000430774 | ENSP00000383366 | Uncharacterized protein; Belongs to the SKP1 family | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.516 |
| GNRH2 | EFCAB8 | ENSP00000245983 | ENSP00000383366 | Progonadoliberin-2; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.441 |
| IL36G | EFCAB8 | ENSP00000259205 | ENSP00000383366 | Interleukin-36 gamma; Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinoc [...] | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.414 |
| KCMF1 | EFCAB8 | ENSP00000386738 | ENSP00000383366 | E3 ubiquitin-protein ligase KCMF1; Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination; Belongs to the KCMF1 family | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.422 |
| SKP1 | EFCAB8 | ENSP00000231487 | ENSP00000383366 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.476 |
| SMIM1 | EFCAB8 | ENSP00000457386 | ENSP00000383366 | Small integral membrane protein 1; Regulator of red blood cell formation; Belongs to the SMIM1 family | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.497 |
| VSTM2L | EFCAB8 | ENSP00000362560 | ENSP00000383366 | V-set and transmembrane domain-containing protein 2-like protein; V-set and transmembrane domain containing 2 like | EF-hand calcium-binding domain-containing protein 8; EF-hand calcium binding domain 8 | 0.642 |
