• Version:
  • 11.0 [archived version]
STRINGSTRING
C15orf53 C15orf53 PCNXL3 PCNXL3 MAP3K7CL MAP3K7CL TAB3 TAB3 USF1 USF1
"MAP3K7CL" - MAP3K7 C-terminal-like protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K7CLMAP3K7 C-terminal-like protein; MAP3K7 C-terminal like (242 aa)    
Predicted Functional Partners:
USF1
Upstream stimulatory factor 1; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters; Basic helix-loop-helix proteins (310 aa)
       
      0.777
TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor; Zinc fingers RANBP2-type (712 aa)
       
      0.547
PCNXL3
Pecanex-like 3 (Drosophila); Belongs to the pecanex family (2034 aa)
           
  0.491
C15orf53
Uncharacterized protein C15orf53; Chromosome 15 open reading frame 53 (179 aa)
           
  0.491
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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