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STRINGSTRING
F7 F7 FAM90A1 FAM90A1 GON4L GON4L ZNF195 ZNF195 SLC45A4 SLC45A4 C3orf55 C3orf55 FAM189B FAM189B TRIM28 TRIM28 PCNX PCNX LCE2D LCE2D ZNF474 ZNF474
"ZNF195" - Zinc finger protein 195 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF195Zinc finger protein 195; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (629 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
      
  0.929
F7
Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium; Gla domain containing (466 aa)
            
  0.800
C3orf55
Putative uncharacterized protein PQLC2L; Chromosome 3 open reading frame 55 (135 aa)
            
  0.588
FAM189B
Protein FAM189B; Family with sequence similarity 189 member B (668 aa)
            
  0.557
FAM90A1
Protein FAM90A1; Family with sequence similarity 90 member A1 (464 aa)
            
  0.530
LCE2D
Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum (110 aa)
            
  0.511
SLC45A4
Solute carrier family 45 member 4; Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family (808 aa)
            
  0.491
ZNF474
Zinc finger protein 474; Zinc fingers C2H2-type (364 aa)
            
  0.473
PCNX
Pecanex-like protein 1; Pecanex homolog (Drosophila); Belongs to the pecanex family (2341 aa)
            
  0.442
GON4L
GON-4-like protein; Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis; Myb/SANT domain containing (2241 aa)
        
 
  0.434
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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