MROH2B protein (human) - STRING database

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MROH2B

Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing (1585 aa)

Predicted Functional Partners:

KPNB1

0.541

OR10A7

0.538

NXPE2

0.530

ASB11

0.522

CADPS2

0.515

TMEM132E

0.512

FRMPD3

0.507

IGSF9B

0.502

TC2N

0.473

SESN2

0.455

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB11	FRMPD3	ENSP00000417914	ENSP00000276185	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	FERM and PDZ domain containing 3	0.542
ASB11	IGSF9B	ENSP00000417914	ENSP00000436552	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing	0.545
ASB11	MROH2B	ENSP00000417914	ENSP00000382476	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	0.522
ASB11	NXPE2	ENSP00000417914	ENSP00000374237	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	NXPE family member 2; Neurexophilin and PC-esterase domain family member 2	0.577
ASB11	TMEM132E	ENSP00000417914	ENSP00000316532	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing; Belongs to the TMEM132 family	0.529
CADPS2	MROH2B	ENSP00000398481	ENSP00000382476	Calcium-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)- dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity); C2 domain containing	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	0.515
FRMPD3	ASB11	ENSP00000276185	ENSP00000417914	FERM and PDZ domain containing 3	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	0.542
FRMPD3	IGSF9B	ENSP00000276185	ENSP00000436552	FERM and PDZ domain containing 3	Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing	0.531
FRMPD3	MROH2B	ENSP00000276185	ENSP00000382476	FERM and PDZ domain containing 3	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	0.507
FRMPD3	NXPE2	ENSP00000276185	ENSP00000374237	FERM and PDZ domain containing 3	NXPE family member 2; Neurexophilin and PC-esterase domain family member 2	0.589
FRMPD3	TMEM132E	ENSP00000276185	ENSP00000316532	FERM and PDZ domain containing 3	Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing; Belongs to the TMEM132 family	0.574
IGSF9B	ASB11	ENSP00000436552	ENSP00000417914	Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	0.545
IGSF9B	FRMPD3	ENSP00000436552	ENSP00000276185	Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing	FERM and PDZ domain containing 3	0.531
IGSF9B	MROH2B	ENSP00000436552	ENSP00000382476	Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	0.502
IGSF9B	NXPE2	ENSP00000436552	ENSP00000374237	Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing	NXPE family member 2; Neurexophilin and PC-esterase domain family member 2	0.546
IGSF9B	TMEM132E	ENSP00000436552	ENSP00000316532	Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing	Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing; Belongs to the TMEM132 family	0.560
KPNB1	MROH2B	ENSP00000290158	ENSP00000382476	Importin subunit beta-1; Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic [...]	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	0.541
MROH2B	ASB11	ENSP00000382476	ENSP00000417914	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	0.522
MROH2B	CADPS2	ENSP00000382476	ENSP00000398481	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	Calcium-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)- dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity); C2 domain containing	0.515
MROH2B	FRMPD3	ENSP00000382476	ENSP00000276185	Maestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation; Maestro heat like repeat containing	FERM and PDZ domain containing 3	0.507

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