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  • 11.0 [archived version]
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DCST1 DCST1 LPHN2 LPHN2 NUP210L NUP210L TCTE1 TCTE1 LPHN3 LPHN3 LRRC56 LRRC56 NATD1 NATD1 LRRC48 LRRC48 LPHN1 LPHN1 MYO15A MYO15A RHBDD2 RHBDD2
"LRRC48" - Dynein regulatory complex subunit 3 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LRRC48Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility (523 aa)    
Predicted Functional Partners:
LPHN3
Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily (1469 aa)
       
      0.683
LPHN1
Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) (1474 aa)
       
      0.683
LPHN2
Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (1403 aa)
       
      0.683
MYO15A
Unconventional myosin-XV; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family (3530 aa)
     
 
  0.636
NATD1
Protein NATD1; N-acetyltransferase domain containing 1 (113 aa)
           
  0.601
NUP210L
Nuclear pore membrane glycoprotein 210-like; Nucleoporin 210 like; Belongs to the NUP210 family (1888 aa)
     
   
  0.600
DCST1
E3 ubiquitin-protein ligase DCST1; E3 ubiquitin-protein ligase which mediates ’Lys-48’- linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling; Ring finger proteins (706 aa)
     
   
  0.586
RHBDD2
Rhomboid domain containing 2; Belongs to the peptidase S54 family (364 aa)
           
  0.578
TCTE1
T-complex-associated-testis-expressed 1; Dynein regulatory complex (501 aa)
           
  0.565
LRRC56
Leucine-rich repeat-containing protein 56; Leucine rich repeat containing 56 (542 aa)
     
   
  0.562
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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