node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DCST1 | LRRC48 | ENSP00000295542 | ENSP00000382140 | E3 ubiquitin-protein ligase DCST1; E3 ubiquitin-protein ligase which mediates ’Lys-48’- linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling; Ring finger proteins | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | 0.586 |
DCST1 | NUP210L | ENSP00000295542 | ENSP00000357547 | E3 ubiquitin-protein ligase DCST1; E3 ubiquitin-protein ligase which mediates ’Lys-48’- linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling; Ring finger proteins | Nuclear pore membrane glycoprotein 210-like; Nucleoporin 210 like; Belongs to the NUP210 family | 0.632 |
DCST1 | TCTE1 | ENSP00000295542 | ENSP00000360560 | E3 ubiquitin-protein ligase DCST1; E3 ubiquitin-protein ligase which mediates ’Lys-48’- linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling; Ring finger proteins | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.604 |
LPHN1 | LRRC48 | ENSP00000340688 | ENSP00000382140 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | 0.683 |
LPHN1 | LRRC56 | ENSP00000340688 | ENSP00000270115 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | Leucine-rich repeat-containing protein 56; Leucine rich repeat containing 56 | 0.683 |
LPHN1 | TCTE1 | ENSP00000340688 | ENSP00000360560 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.685 |
LPHN2 | LRRC48 | ENSP00000322270 | ENSP00000382140 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | 0.683 |
LPHN2 | LRRC56 | ENSP00000322270 | ENSP00000270115 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Leucine-rich repeat-containing protein 56; Leucine rich repeat containing 56 | 0.683 |
LPHN2 | TCTE1 | ENSP00000322270 | ENSP00000360560 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.685 |
LPHN3 | LRRC48 | ENSP00000422533 | ENSP00000382140 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | 0.683 |
LPHN3 | LRRC56 | ENSP00000422533 | ENSP00000270115 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | Leucine-rich repeat-containing protein 56; Leucine rich repeat containing 56 | 0.683 |
LPHN3 | TCTE1 | ENSP00000422533 | ENSP00000360560 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.685 |
LRRC48 | DCST1 | ENSP00000382140 | ENSP00000295542 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | E3 ubiquitin-protein ligase DCST1; E3 ubiquitin-protein ligase which mediates ’Lys-48’- linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling; Ring finger proteins | 0.586 |
LRRC48 | LPHN1 | ENSP00000382140 | ENSP00000340688 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | 0.683 |
LRRC48 | LPHN2 | ENSP00000382140 | ENSP00000322270 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | 0.683 |
LRRC48 | LPHN3 | ENSP00000382140 | ENSP00000422533 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | 0.683 |
LRRC48 | LRRC56 | ENSP00000382140 | ENSP00000270115 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | Leucine-rich repeat-containing protein 56; Leucine rich repeat containing 56 | 0.562 |
LRRC48 | MYO15A | ENSP00000382140 | ENSP00000205890 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | Unconventional myosin-XV; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.636 |
LRRC48 | NATD1 | ENSP00000382140 | ENSP00000478388 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | Protein NATD1; N-acetyltransferase domain containing 1 | 0.601 |
LRRC48 | NUP210L | ENSP00000382140 | ENSP00000357547 | Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility | Nuclear pore membrane glycoprotein 210-like; Nucleoporin 210 like; Belongs to the NUP210 family | 0.600 |