YPEL3 protein (human) - STRING database

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YPEL3

Protein yippee-like 3; Involved in proliferation and apoptosis in myeloid precursor cells; Yippee like family (157 aa)

Predicted Functional Partners:

WDR26

0.716

ASPHD1

0.714

HIRIP3

0.694

FBXL2

0.690

FAM57B

0.683

GDPD3

0.679

C16orf92

0.669

DOC2A

0.639

FBXL20

0.631

KCTD13

0.620

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPHD1	C16orf92	ENSP00000311447	ENSP00000300575	Aspartate beta-hydroxylase domain containing 1	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	0.710
ASPHD1	DOC2A	ENSP00000311447	ENSP00000340017	Aspartate beta-hydroxylase domain containing 1	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	0.772
ASPHD1	FAM57B	ENSP00000311447	ENSP00000369863	Aspartate beta-hydroxylase domain containing 1	Protein FAM57B; Involved in ceramide synthesis; TLC domain containing	0.817
ASPHD1	GDPD3	ENSP00000311447	ENSP00000384363	Aspartate beta-hydroxylase domain containing 1	Lysophospholipase D GDPD3; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine	0.763
ASPHD1	HIRIP3	ENSP00000311447	ENSP00000279392	Aspartate beta-hydroxylase domain containing 1	HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones	0.688
ASPHD1	KCTD13	ENSP00000311447	ENSP00000455785	Aspartate beta-hydroxylase domain containing 1	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity)	0.729
ASPHD1	YPEL3	ENSP00000311447	ENSP00000381821	Aspartate beta-hydroxylase domain containing 1	Protein yippee-like 3; Involved in proliferation and apoptosis in myeloid precursor cells; Yippee like family	0.714
C16orf92	ASPHD1	ENSP00000300575	ENSP00000311447	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	Aspartate beta-hydroxylase domain containing 1	0.710
C16orf92	DOC2A	ENSP00000300575	ENSP00000340017	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	0.588
C16orf92	FAM57B	ENSP00000300575	ENSP00000369863	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	Protein FAM57B; Involved in ceramide synthesis; TLC domain containing	0.669
C16orf92	GDPD3	ENSP00000300575	ENSP00000384363	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	Lysophospholipase D GDPD3; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine	0.630
C16orf92	HIRIP3	ENSP00000300575	ENSP00000279392	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones	0.560
C16orf92	KCTD13	ENSP00000300575	ENSP00000455785	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity)	0.543
C16orf92	YPEL3	ENSP00000300575	ENSP00000381821	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	Protein yippee-like 3; Involved in proliferation and apoptosis in myeloid precursor cells; Yippee like family	0.669
DOC2A	ASPHD1	ENSP00000340017	ENSP00000311447	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	Aspartate beta-hydroxylase domain containing 1	0.772
DOC2A	C16orf92	ENSP00000340017	ENSP00000300575	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92	0.588
DOC2A	FAM57B	ENSP00000340017	ENSP00000369863	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	Protein FAM57B; Involved in ceramide synthesis; TLC domain containing	0.738
DOC2A	GDPD3	ENSP00000340017	ENSP00000384363	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	Lysophospholipase D GDPD3; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine	0.680
DOC2A	HIRIP3	ENSP00000340017	ENSP00000279392	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones	0.715
DOC2A	KCTD13	ENSP00000340017	ENSP00000455785	Double C2-like domain-containing protein alpha; Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; Synaptotagmin like tandem C2 proteins	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity)	0.660

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