node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BSPH1 | C17orf67 | ENSP00000341762 | ENSP00000380959 | Binder of sperm protein homolog 1; Binds sperm in vitro and promotes sperm capacitation. Specifically promotes capacitation induced by high density lipoproteins (HDLs). Also binds heparin, phospholipid liposomes, and weakly to gelatin. Does not bind chondroitin sulfate B | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | 0.685 |
BSPH1 | RUFY1 | ENSP00000341762 | ENSP00000325594 | Binder of sperm protein homolog 1; Binds sperm in vitro and promotes sperm capacitation. Specifically promotes capacitation induced by high density lipoproteins (HDLs). Also binds heparin, phospholipid liposomes, and weakly to gelatin. Does not bind chondroitin sulfate B | RUN and FYVE domain-containing protein 1; Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking; Zinc fingers FYVE-type | 0.507 |
C17orf67 | BSPH1 | ENSP00000380959 | ENSP00000341762 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Binder of sperm protein homolog 1; Binds sperm in vitro and promotes sperm capacitation. Specifically promotes capacitation induced by high density lipoproteins (HDLs). Also binds heparin, phospholipid liposomes, and weakly to gelatin. Does not bind chondroitin sulfate B | 0.685 |
C17orf67 | C3orf67 | ENSP00000380959 | ENSP00000295966 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Uncharacterized protein C3orf67; Chromosome 3 open reading frame 67 | 0.507 |
C17orf67 | C6orf106 | ENSP00000380959 | ENSP00000363135 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Uncharacterized protein C6orf106; Chromosome 6 open reading frame 106 | 0.572 |
C17orf67 | C6orf222 | ENSP00000380959 | ENSP00000418983 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Uncharacterized protein C6orf222; Chromosome 6 open reading frame 222 | 0.507 |
C17orf67 | CABLES1 | ENSP00000380959 | ENSP00000256925 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | CDK5 and ABL1 enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | 0.473 |
C17orf67 | CENPP | ENSP00000380959 | ENSP00000364737 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Centromere protein P; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex; Constitutive centromere associated network | 0.479 |
C17orf67 | FAM101A | ENSP00000380959 | ENSP00000374377 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | 0.615 |
C17orf67 | NUCKS1 | ENSP00000380959 | ENSP00000356110 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Nuclear casein kinase and cyclin dependent kinase substrate 1 | 0.598 |
C17orf67 | POC5 | ENSP00000380959 | ENSP00000410216 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family | 0.580 |
C17orf67 | RUFY1 | ENSP00000380959 | ENSP00000325594 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | RUN and FYVE domain-containing protein 1; Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking; Zinc fingers FYVE-type | 0.595 |
C3orf67 | C17orf67 | ENSP00000295966 | ENSP00000380959 | Uncharacterized protein C3orf67; Chromosome 3 open reading frame 67 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | 0.507 |
C3orf67 | C6orf222 | ENSP00000295966 | ENSP00000418983 | Uncharacterized protein C3orf67; Chromosome 3 open reading frame 67 | Uncharacterized protein C6orf222; Chromosome 6 open reading frame 222 | 0.513 |
C6orf106 | C17orf67 | ENSP00000363135 | ENSP00000380959 | Uncharacterized protein C6orf106; Chromosome 6 open reading frame 106 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | 0.572 |
C6orf106 | CABLES1 | ENSP00000363135 | ENSP00000256925 | Uncharacterized protein C6orf106; Chromosome 6 open reading frame 106 | CDK5 and ABL1 enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | 0.491 |
C6orf222 | C17orf67 | ENSP00000418983 | ENSP00000380959 | Uncharacterized protein C6orf222; Chromosome 6 open reading frame 222 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | 0.507 |
C6orf222 | C3orf67 | ENSP00000418983 | ENSP00000295966 | Uncharacterized protein C6orf222; Chromosome 6 open reading frame 222 | Uncharacterized protein C3orf67; Chromosome 3 open reading frame 67 | 0.513 |
CABLES1 | C17orf67 | ENSP00000256925 | ENSP00000380959 | CDK5 and ABL1 enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | 0.473 |
CABLES1 | C6orf106 | ENSP00000256925 | ENSP00000363135 | CDK5 and ABL1 enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | Uncharacterized protein C6orf106; Chromosome 6 open reading frame 106 | 0.491 |