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  • 11.0 [archived version]
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SERTAD4 SERTAD4 PCGF5 PCGF5 NBEAL1 NBEAL1 YPEL2 YPEL2 YOD1 YOD1 PTPN4 PTPN4 ZBTB44 ZBTB44 NAE1 NAE1 BRWD1 BRWD1 C14orf93 C14orf93 CEP250 CEP250
"ZBTB44" - Zinc finger and BTB domain-containing protein 44 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ZBTB44Zinc finger and BTB domain-containing protein 44; May be involved in transcriptional regulation; BTB domain containing (570 aa)    
Predicted Functional Partners:
C14orf93
Uncharacterized protein C14orf93; Chromosome 14 open reading frame 93 (538 aa)
           
  0.744
NBEAL1
Neurobeachin-like protein 1; Armadillo-like helical domain containing; Belongs to the WD repeat neurobeachin family (2694 aa)
     
   
  0.725
YPEL2
Protein yippee-like 2; Yippee like family (119 aa)
           
  0.687
SERTAD4
SERTA domain containing 4 (356 aa)
           
  0.658
PTPN4
Tyrosine-protein phosphatase non-receptor type 4; May act at junctions between the membrane and the cytoskeleton; Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily (926 aa)
     
 
  0.618
NAE1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation; Ubiquitin like modifier activating enzymes (537 aa)
     
 
  0.559
PCGF5
Polycomb group RING finger protein 5; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. Plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates mon [...] (256 aa)
     
 
  0.514
YOD1
Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP’s axial channel. Mediates deubiquitination of ’Lys-27’-, ’Lys-29’- and ’Lys-33’-linked polyubiquitin chains. A [...] (348 aa)
     
   
  0.501
CEP250
Centrosome-associated protein CEP250; Probably plays an important role in centrosome cohesion during interphase (2442 aa)
           
  0.486
BRWD1
Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing (2320 aa)
     
 
  0.477
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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