ARL16 protein (human) - STRING database

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ARL16

ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family (197 aa)

Predicted Functional Partners:

MON2

0.922

ARL9

0.782

ARFIP2

0.741

ARFIP1

0.741

ARL13A

0.668

FBXO8

0.642

ARFGEF2

0.642

ARFGEF1

0.642

ESPNL

0.630

ARL13B

0.628

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARFGEF1	ARFGEF2	ENSP00000262215	ENSP00000360985	Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and [...]	Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma [...]	0.476
ARFGEF1	ARL16	ENSP00000262215	ENSP00000380635	Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and [...]	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	0.642
ARFGEF2	ARFGEF1	ENSP00000360985	ENSP00000262215	Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma [...]	Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and [...]	0.476
ARFGEF2	ARL16	ENSP00000360985	ENSP00000380635	Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma [...]	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	0.642
ARFIP1	ARFIP2	ENSP00000395083	ENSP00000484121	Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing	Arfaptin-2; Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling; Classical BAR domain containing	0.435
ARFIP1	ARL16	ENSP00000395083	ENSP00000380635	Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	0.741
ARFIP2	ARFIP1	ENSP00000484121	ENSP00000395083	Arfaptin-2; Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling; Classical BAR domain containing	Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing	0.435
ARFIP2	ARL16	ENSP00000484121	ENSP00000380635	Arfaptin-2; Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling; Classical BAR domain containing	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	0.741
ARL13A	ARL16	ENSP00000398637	ENSP00000380635	ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A; ARF GTPase family	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	0.668
ARL13A	ARL9	ENSP00000398637	ENSP00000353210	ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A; ARF GTPase family	ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family	0.733
ARL13B	ARL16	ENSP00000377769	ENSP00000380635	ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development- required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interne [...]	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	0.628
ARL13B	MON2	ENSP00000377769	ENSP00000377250	ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development- required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interne [...]	Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing	0.507
ARL16	ARFGEF1	ENSP00000380635	ENSP00000262215	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and [...]	0.642
ARL16	ARFGEF2	ENSP00000380635	ENSP00000360985	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma [...]	0.642
ARL16	ARFIP1	ENSP00000380635	ENSP00000395083	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing	0.741
ARL16	ARFIP2	ENSP00000380635	ENSP00000484121	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	Arfaptin-2; Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling; Classical BAR domain containing	0.741
ARL16	ARL13A	ENSP00000380635	ENSP00000398637	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A; ARF GTPase family	0.668
ARL16	ARL13B	ENSP00000380635	ENSP00000377769	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development- required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interne [...]	0.628
ARL16	ARL9	ENSP00000380635	ENSP00000353210	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family	0.782
ARL16	ESPNL	ENSP00000380635	ENSP00000339115	ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family	Espin-like protein; Binds to but does not cross-link actin. Required for the formation and maintenance of inner ear hair cell stereocilia and staircase formation. Essential for normal hearing; Ankyrin repeat domain containing	0.630

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