| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CRAMP1L | GON4L | ENSP00000380559 | ENSP00000357315 | Crm, cramped-like (Drosophila) | GON-4-like protein; Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis; Myb/SANT domain containing | 0.854 |
| CRAMP1L | KMT2D | ENSP00000380559 | ENSP00000301067 | Crm, cramped-like (Drosophila) | Histone-lysine N-methyltransferase 2D; Histone methyltransferase. Methylates ’Lys-4’ of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily | 0.650 |
| CRAMP1L | LMOD3 | ENSP00000380559 | ENSP00000414670 | Crm, cramped-like (Drosophila) | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family | 0.719 |
| CRAMP1L | NDUFAF2 | ENSP00000380559 | ENSP00000296597 | Crm, cramped-like (Drosophila) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | 0.695 |
| CRAMP1L | PTX4 | ENSP00000380559 | ENSP00000293922 | Crm, cramped-like (Drosophila) | Pentraxin-4; Long pentraxins | 0.785 |
| CRAMP1L | SDR42E2 | ENSP00000380559 | ENSP00000473474 | Crm, cramped-like (Drosophila) | Short chain dehydrogenase/reductase family 42E, member 2; Belongs to the 3-beta-HSD family | 0.807 |
| CRAMP1L | SMEK2 | ENSP00000380559 | ENSP00000483228 | Crm, cramped-like (Drosophila) | Serine/threonine-protein phosphatase 4 regulatory subunit 3B; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers | 0.719 |
| CRAMP1L | SS18L2 | ENSP00000380559 | ENSP00000401115 | Crm, cramped-like (Drosophila) | SS18-like protein 2; SS18 like 2; Belongs to the SS18 family | 0.840 |
| CRAMP1L | TADA2B | ENSP00000380559 | ENSP00000308022 | Crm, cramped-like (Drosophila) | Transcriptional adapter 2-beta; Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2; Myb/SANT domain containing | 0.713 |
| CRAMP1L | TELO2 | ENSP00000380559 | ENSP00000262319 | Crm, cramped-like (Drosophila) | Telomere length regulation protein TEL2 homolog; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, wh [...] | 0.753 |
| GON4L | CRAMP1L | ENSP00000357315 | ENSP00000380559 | GON-4-like protein; Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis; Myb/SANT domain containing | Crm, cramped-like (Drosophila) | 0.854 |
| KMT2D | CRAMP1L | ENSP00000301067 | ENSP00000380559 | Histone-lysine N-methyltransferase 2D; Histone methyltransferase. Methylates ’Lys-4’ of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily | Crm, cramped-like (Drosophila) | 0.650 |
| LMOD3 | CRAMP1L | ENSP00000414670 | ENSP00000380559 | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family | Crm, cramped-like (Drosophila) | 0.719 |
| LMOD3 | NDUFAF2 | ENSP00000414670 | ENSP00000296597 | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | 0.632 |
| LMOD3 | SDR42E2 | ENSP00000414670 | ENSP00000473474 | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family | Short chain dehydrogenase/reductase family 42E, member 2; Belongs to the 3-beta-HSD family | 0.747 |
| LMOD3 | TADA2B | ENSP00000414670 | ENSP00000308022 | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family | Transcriptional adapter 2-beta; Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2; Myb/SANT domain containing | 0.647 |
| NDUFAF2 | CRAMP1L | ENSP00000296597 | ENSP00000380559 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | Crm, cramped-like (Drosophila) | 0.695 |
| NDUFAF2 | LMOD3 | ENSP00000296597 | ENSP00000414670 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family | 0.632 |
| NDUFAF2 | SDR42E2 | ENSP00000296597 | ENSP00000473474 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | Short chain dehydrogenase/reductase family 42E, member 2; Belongs to the 3-beta-HSD family | 0.771 |
| NDUFAF2 | TADA2B | ENSP00000296597 | ENSP00000308022 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | Transcriptional adapter 2-beta; Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2; Myb/SANT domain containing | 0.675 |
