• Version:
  • 11.0 [archived version]
STRINGSTRING
EFHB EFHB CEACAM21 CEACAM21 LMBRD2 LMBRD2 GTSF1 GTSF1 RAI2 RAI2 CDC42SE2 CDC42SE2 CAPSL CAPSL DEPDC1B DEPDC1B CDH17 CDH17 DNAH9 DNAH9 EFHC1 EFHC1
"CAPSL" - Calcyphosin-like protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPSLCalcyphosin-like protein; EF-hand domain containing (208 aa)    
Predicted Functional Partners:
LMBRD2
LMBR1 domain containing 2 (695 aa)
     
   
  0.738
EFHB
EF-hand domain family member B; Cilia and flagella associated (833 aa)
           
  0.725
DNAH9
Dynein heavy chain 9, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP; Dyneins, axonemal (4486 aa)
           
  0.708
RAI2
Retinoic acid induced 2 (530 aa)
           
  0.696
DEPDC1B
DEP domain containing 1B (529 aa)
           
  0.688
CEACAM21
Carcinoembryonic antigen related cell adhesion molecule family; Belongs to the immunoglobulin superfamily. CEA family (293 aa)
           
  0.670
EFHC1
EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death; EF-hand domain containing (640 aa)
           
  0.644
GTSF1
Gametocyte-specific factor 1; Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells (167 aa)
           
  0.616
CDH17
Cadherin-17; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport (832 aa)
           
  0.603
CDC42SE2
CDC42 small effector protein 2; Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages; Belongs to the CDC42SE/SPEC family (84 aa)
           
  0.589
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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