RPL23L protein (human) - STRING database

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RPL23L

Mitochondrial ribosomal protein L23 (153 aa)

Predicted Functional Partners:

MRPL47

0.995

MRPL41

0.995

MRPL4

0.994

MRPL3

0.992

MRPL44

0.988

MRPL15

0.986

MRPL13

0.983

MRPS10

0.982

ICT1

0.980

MRPS14

0.979

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ICT1	MRPL13	ENSP00000301585	ENSP00000306548	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	0.998
ICT1	MRPL15	ENSP00000301585	ENSP00000260102	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L15	0.995
ICT1	MRPL3	ENSP00000301585	ENSP00000264995	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L3	0.999
ICT1	MRPL4	ENSP00000301585	ENSP00000253099	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family	0.997
ICT1	MRPL41	ENSP00000301585	ENSP00000360498	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins	0.998
ICT1	MRPL44	ENSP00000301585	ENSP00000258383	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins	0.994
ICT1	MRPL47	ENSP00000301585	ENSP00000417602	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L47	0.998
ICT1	MRPS10	ENSP00000301585	ENSP00000053468	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family	0.996
ICT1	MRPS14	ENSP00000301585	ENSP00000420714	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein S14; Belongs to the universal ribosomal protein uS14 family	0.994
ICT1	RPL23L	ENSP00000301585	ENSP00000380466	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L23	0.980
MRPL13	ICT1	ENSP00000306548	ENSP00000301585	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	0.998
MRPL13	MRPL15	ENSP00000306548	ENSP00000260102	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L15	0.999
MRPL13	MRPL3	ENSP00000306548	ENSP00000264995	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L3	0.999
MRPL13	MRPL4	ENSP00000306548	ENSP00000253099	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family	0.999
MRPL13	MRPL41	ENSP00000306548	ENSP00000360498	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins	0.999
MRPL13	MRPL44	ENSP00000306548	ENSP00000258383	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins	0.999
MRPL13	MRPL47	ENSP00000306548	ENSP00000417602	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L47	0.999
MRPL13	MRPS10	ENSP00000306548	ENSP00000053468	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family	0.999
MRPL13	MRPS14	ENSP00000306548	ENSP00000420714	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein S14; Belongs to the universal ribosomal protein uS14 family	0.997
MRPL13	RPL23L	ENSP00000306548	ENSP00000380466	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L23	0.983

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