CCDC125 protein (human) - STRING database

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CCDC125

Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration (511 aa)

Predicted Functional Partners:

PPP1R36

0.669

PPIL3

0.539

RASL11B

0.484

AEN

0.478

PPAPDC1B

0.464

TACC1

0.461

FOXS1

0.426

TIMM8A

0.424

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEN	CCDC125	ENSP00000331944	ENSP00000379754	Apoptosis-enhancing nuclease; Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis; Exonucleases	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	0.478
AEN	RASL11B	ENSP00000331944	ENSP00000248706	Apoptosis-enhancing nuclease; Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis; Exonucleases	Ras-like protein family member 11B; RAS like family 11 member B	0.466
CCDC125	AEN	ENSP00000379754	ENSP00000331944	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Apoptosis-enhancing nuclease; Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis; Exonucleases	0.478
CCDC125	FOXS1	ENSP00000379754	ENSP00000365145	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes	0.426
CCDC125	PPAPDC1B	ENSP00000379754	ENSP00000392553	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Phospholipid phosphatase 5; Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma	0.464
CCDC125	PPIL3	ENSP00000379754	ENSP00000286175	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases	0.539
CCDC125	PPP1R36	ENSP00000379754	ENSP00000298705	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes	0.669
CCDC125	RASL11B	ENSP00000379754	ENSP00000248706	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Ras-like protein family member 11B; RAS like family 11 member B	0.484
CCDC125	TACC1	ENSP00000379754	ENSP00000321703	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Transforming acidic coiled-coil-containing protein 1; Likely involved in the processes that promote cell division prior to the formation of differentiated tissues	0.461
CCDC125	TIMM8A	ENSP00000379754	ENSP00000361993	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	Mitochondrial import inner membrane translocase subunit Tim8 A; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins [...]	0.424
FOXS1	CCDC125	ENSP00000365145	ENSP00000379754	Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	0.426
FOXS1	PPP1R36	ENSP00000365145	ENSP00000298705	Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes	Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes	0.530
PPAPDC1B	CCDC125	ENSP00000392553	ENSP00000379754	Phospholipid phosphatase 5; Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	0.464
PPAPDC1B	PPIL3	ENSP00000392553	ENSP00000286175	Phospholipid phosphatase 5; Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases	0.418
PPIL3	CCDC125	ENSP00000286175	ENSP00000379754	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	0.539
PPIL3	PPAPDC1B	ENSP00000286175	ENSP00000392553	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases	Phospholipid phosphatase 5; Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma	0.418
PPIL3	TIMM8A	ENSP00000286175	ENSP00000361993	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases	Mitochondrial import inner membrane translocase subunit Tim8 A; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins [...]	0.477
PPP1R36	CCDC125	ENSP00000298705	ENSP00000379754	Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes	Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration	0.669
PPP1R36	FOXS1	ENSP00000298705	ENSP00000365145	Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes	Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes	0.530
RASL11B	AEN	ENSP00000248706	ENSP00000331944	Ras-like protein family member 11B; RAS like family 11 member B	Apoptosis-enhancing nuclease; Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis; Exonucleases	0.466

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