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  • 11.0 [archived version]
STRINGSTRING
DBNDD2 DBNDD2 NTAN1 NTAN1 RCC2 RCC2 WDR27 WDR27 MYO1D MYO1D PDXDC1 PDXDC1 CXorf56 CXorf56 KIAA2013 KIAA2013 PPP1R26 PPP1R26 NOMO1 NOMO1 BFAR BFAR
"PDXDC1" - Pyridoxal-dependent decarboxylase domain-containing protein 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PDXDC1Pyridoxal-dependent decarboxylase domain-containing protein 1; Pyridoxal dependent decarboxylase domain containing 1; Belongs to the group II decarboxylase family (788 aa)    
Predicted Functional Partners:
BFAR
Bifunctional apoptosis regulator; Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors; Ring finger proteins (450 aa)
            
  0.905
NOMO1
Nodal modulator 1; May antagonize Nodal signaling (1222 aa)
      
   
  0.903
DBNDD2
Dysbindin domain-containing protein 2; May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro); Belongs to the dysbindin family (263 aa)
            
  0.742
NTAN1
Protein N-terminal asparagine amidohydrolase; Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N- terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme doe [...] (310 aa)
            
  0.720
PPP1R26
Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation (1209 aa)
            
  0.699
KIAA2013
Uncharacterized protein KIAA2013; KIAA2013 (634 aa)
            
  0.693
WDR27
WD repeat-containing protein 27; WD repeat domain containing (895 aa)
            
  0.689
CXorf56
UPF0428 protein CXorf56; Chromosome X open reading frame 56; Spliceosomal C complex (208 aa)
      
   
  0.682
MYO1D
Unconventional myosin-Id; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity); Myosins, class I (1006 aa)
      
   
  0.663
RCC2
Protein RCC2; Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1 (522 aa)
            
  0.656
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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