| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANTXRL | SEPSECS | ENSP00000480615 | ENSP00000371535 | Anthrax toxin receptor like | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis | 0.562 |
| ANTXRL | TRIM59 | ENSP00000480615 | ENSP00000311219 | Anthrax toxin receptor like | Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways; Ring finger proteins | 0.531 |
| ANTXRL | TSEN2 | ENSP00000480615 | ENSP00000284995 | Anthrax toxin receptor like | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | 0.596 |
| ANTXRL | ZNF813 | ENSP00000480615 | ENSP00000379684 | Anthrax toxin receptor like | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.656 |
| ANTXRL | ZYG11B | ENSP00000480615 | ENSP00000294353 | Anthrax toxin receptor like | Protein zyg-11 homolog B; Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC; Armadillo-like helical domain containing | 0.707 |
| CCT8L2 | ZNF813 | ENSP00000353048 | ENSP00000379684 | T-complex protein 1 subunit theta-like 2; Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis; Belongs to the TCP-1 chaperonin family | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.410 |
| CELF5 | ENTPD6 | ENSP00000292672 | ENSP00000365840 | CUGBP Elav-like family member 5; RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA | Ectonucleoside triphosphate diphosphohydrolase 6; Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5’-diphosphates, nucleoside 5’-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5’-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP (By similarity); Belongs to the GDA1/CD39 NTPase family | 0.536 |
| CELF5 | ZNF813 | ENSP00000292672 | ENSP00000379684 | CUGBP Elav-like family member 5; RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.453 |
| ENTPD6 | CELF5 | ENSP00000365840 | ENSP00000292672 | Ectonucleoside triphosphate diphosphohydrolase 6; Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5’-diphosphates, nucleoside 5’-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5’-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP (By similarity); Belongs to the GDA1/CD39 NTPase family | CUGBP Elav-like family member 5; RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA | 0.536 |
| ENTPD6 | ZNF813 | ENSP00000365840 | ENSP00000379684 | Ectonucleoside triphosphate diphosphohydrolase 6; Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5’-diphosphates, nucleoside 5’-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5’-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP (By similarity); Belongs to the GDA1/CD39 NTPase family | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.479 |
| SEPSECS | ANTXRL | ENSP00000371535 | ENSP00000480615 | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis | Anthrax toxin receptor like | 0.562 |
| SEPSECS | TSEN2 | ENSP00000371535 | ENSP00000284995 | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | 0.559 |
| SEPSECS | ZNF813 | ENSP00000371535 | ENSP00000379684 | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.422 |
| SEPSECS | ZYG11B | ENSP00000371535 | ENSP00000294353 | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis | Protein zyg-11 homolog B; Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC; Armadillo-like helical domain containing | 0.537 |
| TRIM59 | ANTXRL | ENSP00000311219 | ENSP00000480615 | Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways; Ring finger proteins | Anthrax toxin receptor like | 0.531 |
| TRIM59 | ZNF813 | ENSP00000311219 | ENSP00000379684 | Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways; Ring finger proteins | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.455 |
| TRIM59 | ZYG11B | ENSP00000311219 | ENSP00000294353 | Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways; Ring finger proteins | Protein zyg-11 homolog B; Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC; Armadillo-like helical domain containing | 0.493 |
| TSEN2 | ANTXRL | ENSP00000284995 | ENSP00000480615 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | Anthrax toxin receptor like | 0.596 |
| TSEN2 | SEPSECS | ENSP00000284995 | ENSP00000371535 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis | 0.559 |
| TSEN2 | ZNF813 | ENSP00000284995 | ENSP00000379684 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’- and 3’-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’-cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.440 |
