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  • 11.0 [archived version]
STRINGSTRING
MYL9 MYL9 ACTG2 ACTG2 MYL6B MYL6B ACTA2 ACTA2 MYL6 MYL6 MYL12B MYL12B MYL10 MYL10 MYL12A MYL12A MYH11 MYH11 MYLPF MYLPF MYLK MYLK
"MYH11" - Myosin-11 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MYH11Myosin-11; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family (1979 aa)    
Predicted Functional Partners:
ACTA2
Actin, aortic smooth muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family (377 aa)
      
  0.993
ACTG2
Actin, gamma-enteric smooth muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (376 aa)
      
  0.986
MYL12B
Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing (172 aa)
      
  0.985
MYL9
Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing (172 aa)
      
  0.982
MYL12A
Myosin regulatory light chain 12A; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity); EF-hand domain containing (171 aa)
      
  0.979
MYLK
Myosin light chain kinase, smooth muscle; Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological [...] (1914 aa)
      
  0.978
MYL6
Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing (151 aa)
        
  0.978
MYL6B
Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing (208 aa)
        
  0.977
MYLPF
Myosin light chain, phosphorylatable, fast skeletal muscle; EF-hand domain containing (169 aa)
      
  0.976
MYL10
Myosin regulatory light chain 10; EF-hand domain containing (226 aa)
      
  0.976
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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