| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FLI1 | ZNF35 | ENSP00000433488 | ENSP00000379368 | Friend leukemia integration 1 transcription factor; Sequence-specific transcriptional activator. Recognizes the DNA sequence 5’-C[CA]GGAAGT-3’; Belongs to the ETS family | Zinc finger protein 35; May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation; Zinc fingers C2H2-type | 0.492 |
| L3MBTL2 | RBM14 | ENSP00000216237 | ENSP00000311747 | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ’Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ’Lys-4’, ’Lys-9’ or ’Lys-27’; MBT domain containing | RNA-binding protein 14; Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) [...] | 0.518 |
| L3MBTL2 | TAF6L | ENSP00000216237 | ENSP00000294168 | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ’Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ’Lys-4’, ’Lys-9’ or ’Lys-27’; MBT domain containing | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex; Belongs to the TAF6 family | 0.628 |
| L3MBTL2 | TFAP4 | ENSP00000216237 | ENSP00000204517 | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ’Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ’Lys-4’, ’Lys-9’ or ’Lys-27’; MBT domain containing | Transcription factor AP-4; Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5’- CAGCTG-3’; Basic helix-loop-helix proteins | 0.491 |
| L3MBTL2 | ZNF35 | ENSP00000216237 | ENSP00000379368 | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ’Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ’Lys-4’, ’Lys-9’ or ’Lys-27’; MBT domain containing | Zinc finger protein 35; May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation; Zinc fingers C2H2-type | 0.530 |
| OR2AT4 | SLC22A14 | ENSP00000304846 | ENSP00000273173 | Olfactory receptor 2AT4; Odorant receptor; Olfactory receptors, family 2 | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | 0.519 |
| OR2AT4 | YEATS2 | ENSP00000304846 | ENSP00000306983 | Olfactory receptor 2AT4; Odorant receptor; Olfactory receptors, family 2 | YEATS domain-containing protein 2; Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at ’Lys-27’ (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors | 0.452 |
| OR2AT4 | ZNF35 | ENSP00000304846 | ENSP00000379368 | Olfactory receptor 2AT4; Odorant receptor; Olfactory receptors, family 2 | Zinc finger protein 35; May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation; Zinc fingers C2H2-type | 0.526 |
| OR52B4 | SLC22A14 | ENSP00000485078 | ENSP00000273173 | Olfactory receptor 52B4; Odorant receptor; Olfactory receptors, family 52 | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | 0.521 |
| OR52B4 | YEATS2 | ENSP00000485078 | ENSP00000306983 | Olfactory receptor 52B4; Odorant receptor; Olfactory receptors, family 52 | YEATS domain-containing protein 2; Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at ’Lys-27’ (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors | 0.453 |
| OR52B4 | ZNF35 | ENSP00000485078 | ENSP00000379368 | Olfactory receptor 52B4; Odorant receptor; Olfactory receptors, family 52 | Zinc finger protein 35; May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation; Zinc fingers C2H2-type | 0.526 |
| RBM14 | L3MBTL2 | ENSP00000311747 | ENSP00000216237 | RNA-binding protein 14; Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) [...] | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ’Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ’Lys-4’, ’Lys-9’ or ’Lys-27’; MBT domain containing | 0.518 |
| RBM14 | TAF6L | ENSP00000311747 | ENSP00000294168 | RNA-binding protein 14; Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) [...] | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex; Belongs to the TAF6 family | 0.623 |
| RBM14 | TFAP4 | ENSP00000311747 | ENSP00000204517 | RNA-binding protein 14; Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) [...] | Transcription factor AP-4; Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5’- CAGCTG-3’; Basic helix-loop-helix proteins | 0.435 |
| RBM14 | ZNF35 | ENSP00000311747 | ENSP00000379368 | RNA-binding protein 14; Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) [...] | Zinc finger protein 35; May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation; Zinc fingers C2H2-type | 0.470 |
| SLC22A14 | OR2AT4 | ENSP00000273173 | ENSP00000304846 | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | Olfactory receptor 2AT4; Odorant receptor; Olfactory receptors, family 2 | 0.519 |
| SLC22A14 | OR52B4 | ENSP00000273173 | ENSP00000485078 | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | Olfactory receptor 52B4; Odorant receptor; Olfactory receptors, family 52 | 0.521 |
| SLC22A14 | YEATS2 | ENSP00000273173 | ENSP00000306983 | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | YEATS domain-containing protein 2; Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at ’Lys-27’ (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors | 0.449 |
| SLC22A14 | ZNF35 | ENSP00000273173 | ENSP00000379368 | Solute carrier family 22 member 14; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | Zinc finger protein 35; May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation; Zinc fingers C2H2-type | 0.534 |
| TAF6L | L3MBTL2 | ENSP00000294168 | ENSP00000216237 | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex; Belongs to the TAF6 family | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ’Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ’Lys-4’, ’Lys-9’ or ’Lys-27’; MBT domain containing | 0.628 |
