node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A4GALT | CASC1 | ENSP00000384794 | ENSP00000379310 | Lactosylceramide 4-alpha-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins; Alpha 1,4-glycosyltransferases | Protein phosphatase 1 regulatory subunits | 0.625 |
A4GALT | FN3K | ENSP00000384794 | ENSP00000300784 | Lactosylceramide 4-alpha-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins; Alpha 1,4-glycosyltransferases | Fructosamine-3-kinase; May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme | 0.526 |
A4GALT | FN3KRP | ENSP00000384794 | ENSP00000269373 | Lactosylceramide 4-alpha-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins; Alpha 1,4-glycosyltransferases | Ketosamine-3-kinase; Phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein- bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation | 0.611 |
A4GALT | RIOK2 | ENSP00000384794 | ENSP00000283109 | Lactosylceramide 4-alpha-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins; Alpha 1,4-glycosyltransferases | Serine/threonine-protein kinase RIO2; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre- ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its catalytic activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre- rRNA to the mature 18S rRNA | 0.534 |
CASC1 | A4GALT | ENSP00000379310 | ENSP00000384794 | Protein phosphatase 1 regulatory subunits | Lactosylceramide 4-alpha-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins; Alpha 1,4-glycosyltransferases | 0.625 |
CASC1 | CASC4 | ENSP00000379310 | ENSP00000299957 | Protein phosphatase 1 regulatory subunits | Protein CASC4; Cancer susceptibility 4; Belongs to the GOLM1/CASC4 family | 0.620 |
CASC1 | CCDC18 | ENSP00000379310 | ENSP00000383808 | Protein phosphatase 1 regulatory subunits | Coiled-coil domain containing 18 | 0.669 |
CASC1 | CFAP36 | ENSP00000379310 | ENSP00000342699 | Protein phosphatase 1 regulatory subunits | Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family | 0.648 |
CASC1 | FN3K | ENSP00000379310 | ENSP00000300784 | Protein phosphatase 1 regulatory subunits | Fructosamine-3-kinase; May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme | 0.621 |
CASC1 | FN3KRP | ENSP00000379310 | ENSP00000269373 | Protein phosphatase 1 regulatory subunits | Ketosamine-3-kinase; Phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein- bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation | 0.743 |
CASC1 | LMNTD1 | ENSP00000379310 | ENSP00000407353 | Protein phosphatase 1 regulatory subunits | Lamin tail domain containing 1 | 0.684 |
CASC1 | LRMP | ENSP00000379310 | ENSP00000346442 | Protein phosphatase 1 regulatory subunits | Lymphoid-restricted membrane protein; Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion | 0.719 |
CASC1 | LYRM5 | ENSP00000379310 | ENSP00000370761 | Protein phosphatase 1 regulatory subunits | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB) | 0.655 |
CASC1 | RIOK2 | ENSP00000379310 | ENSP00000283109 | Protein phosphatase 1 regulatory subunits | Serine/threonine-protein kinase RIO2; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre- ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its catalytic activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre- rRNA to the mature 18S rRNA | 0.711 |
CASC4 | CASC1 | ENSP00000299957 | ENSP00000379310 | Protein CASC4; Cancer susceptibility 4; Belongs to the GOLM1/CASC4 family | Protein phosphatase 1 regulatory subunits | 0.620 |
CCDC18 | CASC1 | ENSP00000383808 | ENSP00000379310 | Coiled-coil domain containing 18 | Protein phosphatase 1 regulatory subunits | 0.669 |
CCDC18 | CFAP36 | ENSP00000383808 | ENSP00000342699 | Coiled-coil domain containing 18 | Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family | 0.712 |
CFAP36 | CASC1 | ENSP00000342699 | ENSP00000379310 | Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family | Protein phosphatase 1 regulatory subunits | 0.648 |
CFAP36 | CCDC18 | ENSP00000342699 | ENSP00000383808 | Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family | Coiled-coil domain containing 18 | 0.712 |
FN3K | A4GALT | ENSP00000300784 | ENSP00000384794 | Fructosamine-3-kinase; May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme | Lactosylceramide 4-alpha-galactosyltransferase; Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins; Alpha 1,4-glycosyltransferases | 0.526 |