• Version:
  • 11.0 [archived version]
STRINGSTRING
PATE1 PATE1 FOXRED2 FOXRED2 PCYOX1 PCYOX1 PLAC8L1 PLAC8L1 FKBP7 FKBP7 FAM172A FAM172A ERP27 ERP27 GRIK3 GRIK3 POGLUT1 POGLUT1 CNPY3 CNPY3 AGR3 AGR3
"FAM172A" - Protein FAM172A in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
FAM172AProtein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family (416 aa)    
Predicted Functional Partners:
PLAC8L1
PLAC8-like protein 1; PLAC8 like 1; Belongs to the cornifelin family (177 aa)
           
  0.769
GRIK3
Glutamate receptor ionotropic, kainate 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA (919 aa)
           
  0.653
PCYOX1
Prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (505 aa)
           
  0.628
CNPY3
Protein canopy homolog 3; Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity); Belongs to the canopy family (278 aa)
           
  0.622
POGLUT1
Protein O-glucosyltransferase 1; Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation- acts by mediating O- g [...] (392 aa)
           
  0.604
AGR3
Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family (166 aa)
           
  0.604
FOXRED2
FAD-dependent oxidoreductase domain-containing protein 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (684 aa)
           
  0.602
ERP27
Endoplasmic reticulum protein 27; Belongs to the protein disulfide isomerase family (273 aa)
           
  0.596
FKBP7
Peptidylprolyl isomerase; EF-hand domain containing (222 aa)
           
  0.593
PATE1
Prostate and testis expressed 1; Belongs to the PATE family (126 aa)
           
  0.580
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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