| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCAS1 | CDC5L | ENSP00000379290 | ENSP00000360532 | Breast carcinoma amplified sequence 1 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | 0.562 |
| BCAS1 | ENPP6 | ENSP00000379290 | ENSP00000296741 | Breast carcinoma amplified sequence 1 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin (By similarity). Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12-0 and 14-0) or polyunsaturated (18-2 and 20-4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipa [...] | 0.550 |
| BCAS1 | GFAP | ENSP00000379290 | ENSP00000468500 | Breast carcinoma amplified sequence 1 | Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells | 0.597 |
| BCAS1 | OMG | ENSP00000379290 | ENSP00000247271 | Breast carcinoma amplified sequence 1 | Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system | 0.556 |
| BCAS1 | PLLP | ENSP00000379290 | ENSP00000219207 | Breast carcinoma amplified sequence 1 | Plasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity); Belongs to the MAL family | 0.559 |
| BCAS1 | PLP1 | ENSP00000379290 | ENSP00000481006 | Breast carcinoma amplified sequence 1 | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin; Belongs to the myelin proteolipid protein family | 0.718 |
| BCAS1 | PLRG1 | ENSP00000379290 | ENSP00000424417 | Breast carcinoma amplified sequence 1 | Pleiotropic regulator 1; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing | 0.580 |
| BCAS1 | QKI | ENSP00000379290 | ENSP00000355094 | Breast carcinoma amplified sequence 1 | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5’-NACUAAY-N(1,20)- UAAY-3’ RNA core sequence. Regulates target mRNA stability. In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulat [...] | 0.669 |
| BCAS1 | SCRG1 | ENSP00000379290 | ENSP00000296506 | Breast carcinoma amplified sequence 1 | Scrapie-responsive protein 1; Stimulator of chondrogenesis 1 | 0.544 |
| BCAS1 | ZNF217 | ENSP00000379290 | ENSP00000360526 | Breast carcinoma amplified sequence 1 | Zinc finger protein 217; Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at ’Ser-473’; Zinc fingers C2H2-type | 0.630 |
| CDC5L | BCAS1 | ENSP00000360532 | ENSP00000379290 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | Breast carcinoma amplified sequence 1 | 0.562 |
| CDC5L | PLRG1 | ENSP00000360532 | ENSP00000424417 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing | Pleiotropic regulator 1; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing | 0.999 |
| ENPP6 | BCAS1 | ENSP00000296741 | ENSP00000379290 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin (By similarity). Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12-0 and 14-0) or polyunsaturated (18-2 and 20-4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipa [...] | Breast carcinoma amplified sequence 1 | 0.550 |
| GFAP | BCAS1 | ENSP00000468500 | ENSP00000379290 | Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells | Breast carcinoma amplified sequence 1 | 0.597 |
| GFAP | OMG | ENSP00000468500 | ENSP00000247271 | Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells | Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system | 0.723 |
| GFAP | PLLP | ENSP00000468500 | ENSP00000219207 | Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells | Plasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity); Belongs to the MAL family | 0.548 |
| GFAP | PLP1 | ENSP00000468500 | ENSP00000481006 | Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin; Belongs to the myelin proteolipid protein family | 0.831 |
| GFAP | SCRG1 | ENSP00000468500 | ENSP00000296506 | Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells | Scrapie-responsive protein 1; Stimulator of chondrogenesis 1 | 0.604 |
| OMG | BCAS1 | ENSP00000247271 | ENSP00000379290 | Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system | Breast carcinoma amplified sequence 1 | 0.556 |
| OMG | GFAP | ENSP00000247271 | ENSP00000468500 | Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system | Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells | 0.723 |
