node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD12 | ABHD16A | ENSP00000365725 | ENSP00000379282 | Monoacylglycerol lipase ABHD12; Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways; Abhydrolase domain containing | Protein ABHD16A; Abhydrolase domain containing 16A | 0.608 |
ABHD13 | ABHD16A | ENSP00000365063 | ENSP00000379282 | Protein ABHD13; Abhydrolase domain containing 13 | Protein ABHD16A; Abhydrolase domain containing 16A | 0.663 |
ABHD16A | ABHD12 | ENSP00000379282 | ENSP00000365725 | Protein ABHD16A; Abhydrolase domain containing 16A | Monoacylglycerol lipase ABHD12; Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways; Abhydrolase domain containing | 0.608 |
ABHD16A | ABHD13 | ENSP00000379282 | ENSP00000365063 | Protein ABHD16A; Abhydrolase domain containing 16A | Protein ABHD13; Abhydrolase domain containing 13 | 0.663 |
ABHD16A | DDX39B | ENSP00000379282 | ENSP00000379475 | Protein ABHD16A; Abhydrolase domain containing 16A | Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pa [...] | 0.648 |
ABHD16A | GPANK1 | ENSP00000379282 | ENSP00000365071 | Protein ABHD16A; Abhydrolase domain containing 16A | G-patch domain and ankyrin repeats 1 | 0.883 |
ABHD16A | LST1 | ENSP00000379282 | ENSP00000365261 | Protein ABHD16A; Abhydrolase domain containing 16A | Leukocyte-specific transcript 1 protein; Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation | 0.711 |
ABHD16A | LTA | ENSP00000379282 | ENSP00000403495 | Protein ABHD16A; Abhydrolase domain containing 16A | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo; Tumor necrosis factor superfamily | 0.752 |
ABHD16A | LY6G5C | ENSP00000379282 | ENSP00000372724 | Protein ABHD16A; Abhydrolase domain containing 16A | Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation; LY6/PLAUR domain containing | 0.595 |
ABHD16A | PRRC2A | ENSP00000379282 | ENSP00000365201 | Protein ABHD16A; Abhydrolase domain containing 16A | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | 0.748 |
ABHD16A | RNF5 | ENSP00000379282 | ENSP00000364235 | Protein ABHD16A; Abhydrolase domain containing 16A | E3 ubiquitin-protein ligase RNF5; Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the ’Lys-63’-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Me [...] | 0.639 |
ABHD16A | ZBTB12 | ENSP00000379282 | ENSP00000364677 | Protein ABHD16A; Abhydrolase domain containing 16A | Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing | 0.755 |
DDX39B | ABHD16A | ENSP00000379475 | ENSP00000379282 | Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pa [...] | Protein ABHD16A; Abhydrolase domain containing 16A | 0.648 |
DDX39B | LST1 | ENSP00000379475 | ENSP00000365261 | Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pa [...] | Leukocyte-specific transcript 1 protein; Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation | 0.641 |
DDX39B | PRRC2A | ENSP00000379475 | ENSP00000365201 | Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pa [...] | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | 0.426 |
GPANK1 | ABHD16A | ENSP00000365071 | ENSP00000379282 | G-patch domain and ankyrin repeats 1 | Protein ABHD16A; Abhydrolase domain containing 16A | 0.883 |
GPANK1 | LY6G5C | ENSP00000365071 | ENSP00000372724 | G-patch domain and ankyrin repeats 1 | Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation; LY6/PLAUR domain containing | 0.536 |
GPANK1 | PRRC2A | ENSP00000365071 | ENSP00000365201 | G-patch domain and ankyrin repeats 1 | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing | 0.794 |
GPANK1 | ZBTB12 | ENSP00000365071 | ENSP00000364677 | G-patch domain and ankyrin repeats 1 | Zinc finger and BTB domain-containing protein 12; May be involved in transcriptional regulation; BTB domain containing | 0.804 |
LST1 | ABHD16A | ENSP00000365261 | ENSP00000379282 | Leukocyte-specific transcript 1 protein; Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation | Protein ABHD16A; Abhydrolase domain containing 16A | 0.711 |