TEKT3 protein (human) - STRING database

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TEKT3

Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins (490 aa)

Predicted Functional Partners:

ROPN1L

0.700

CCDC63

0.657

CFAP36

0.641

CD164L2

0.639

CAPZA3

0.622

RIBC2

0.602

TTC29

0.600

CDRT4

0.596

CEP112

0.589

EFHC1

0.569

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAPZA3	TEKT3	ENSP00000326238	ENSP00000379263	F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity)	Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins	0.622
CCDC63	CFAP36	ENSP00000312399	ENSP00000342699	Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads	Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family	0.740
CCDC63	RIBC2	ENSP00000312399	ENSP00000483356	Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads	RIB43A domain with coiled-coils 2	0.725
CCDC63	ROPN1L	ENSP00000312399	ENSP00000421405	Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation	0.728
CCDC63	TEKT3	ENSP00000312399	ENSP00000379263	Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads	Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins	0.657
CCDC63	TTC29	ENSP00000312399	ENSP00000423505	Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads	Tetratricopeptide repeat domain containing	0.700
CD164L2	TEKT3	ENSP00000363139	ENSP00000379263	CD164 molecule like 2; Belongs to the CD164 family	Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins	0.639
CDRT4	TEKT3	ENSP00000482523	ENSP00000379263	CMT1A duplicated region transcript 4	Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins	0.596
CEP112	TEKT3	ENSP00000376522	ENSP00000379263	Centrosomal protein 112	Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins	0.589
CEP112	TTC29	ENSP00000376522	ENSP00000423505	Centrosomal protein 112	Tetratricopeptide repeat domain containing	0.861
CFAP36	CCDC63	ENSP00000342699	ENSP00000312399	Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family	Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads	0.740
CFAP36	RIBC2	ENSP00000342699	ENSP00000483356	Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family	RIB43A domain with coiled-coils 2	0.712
CFAP36	ROPN1L	ENSP00000342699	ENSP00000421405	Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation	0.674
CFAP36	TEKT3	ENSP00000342699	ENSP00000379263	Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family	Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins	0.641
CFAP36	TTC29	ENSP00000342699	ENSP00000423505	Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family	Tetratricopeptide repeat domain containing	0.746
EFHC1	RIBC2	ENSP00000360107	ENSP00000483356	EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death; EF-hand domain containing	RIB43A domain with coiled-coils 2	0.489
EFHC1	TEKT3	ENSP00000360107	ENSP00000379263	EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death; EF-hand domain containing	Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins	0.569
RIBC2	CCDC63	ENSP00000483356	ENSP00000312399	RIB43A domain with coiled-coils 2	Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads	0.725
RIBC2	CFAP36	ENSP00000483356	ENSP00000342699	RIB43A domain with coiled-coils 2	Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family	0.712
RIBC2	EFHC1	ENSP00000483356	ENSP00000360107	RIB43A domain with coiled-coils 2	EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death; EF-hand domain containing	0.489

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