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STRINGSTRING
STOML2 STOML2 TMA7 TMA7 ZNF714 ZNF714 PCDHGB2 PCDHGB2 CCDC51 CCDC51 SSBP3 SSBP3 ARHGAP23 ARHGAP23 ZNF541 ZNF541 LAMP5 LAMP5 PALD1 PALD1 ADAMTS18 ADAMTS18
"CCDC51" - Coiled-coil domain containing 51 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
CCDC51Coiled-coil domain containing 51 (411 aa)    
Predicted Functional Partners:
ZNF541
Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis; Myb/SANT domain containing (1346 aa)
            
  0.832
ARHGAP23
Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state; PDZ domain containing (1491 aa)
            
  0.808
PALD1
Paladin; Phosphatase domain containing, paladin 1 (856 aa)
            
  0.714
TMA7
Translation machinery associated 7 homolog (64 aa)
      
   
  0.682
SSBP3
Single-stranded DNA-binding protein 3; May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region (388 aa)
            
  0.661
LAMP5
Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain (280 aa)
            
  0.620
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif 18 (1221 aa)
            
  0.583
PCDHGB2
Protocadherin gamma-B2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (931 aa)
            
  0.556
ZNF714
Zinc finger protein 714; May be involved in transcriptional regulation; Zinc fingers C2H2-type (555 aa)
            
  0.539
STOML2
Stomatin-like protein 2, mitochondrial; Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. M [...] (356 aa)
      
   
  0.487
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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