DHRS7B protein (human) - STRING database

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DHRS7B

Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily (325 aa)

Predicted Functional Partners:

RAB7A

0.870

RAB1B

0.828

TMEM11

0.640

NATD1

0.604

PRR7

0.594

SPATA2L

0.539

GPATCH2L

0.538

DNAJC8

0.536

LRRC48

0.503

CSRP2

0.486

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSRP2	DHRS7B	ENSP00000310901	ENSP00000378887	Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system; LIM domain containing	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	0.486
DHRS7B	CSRP2	ENSP00000378887	ENSP00000310901	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system; LIM domain containing	0.486
DHRS7B	DNAJC8	ENSP00000378887	ENSP00000263697	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	DnaJ homolog subfamily C member 8; Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells; DNAJ heat shock proteins	0.536
DHRS7B	GPATCH2L	ENSP00000378887	ENSP00000261530	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	G patch domain-containing protein 2-like; G-patch domain containing 2 like	0.538
DHRS7B	LRRC48	ENSP00000378887	ENSP00000382140	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility	0.503
DHRS7B	NATD1	ENSP00000378887	ENSP00000478388	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Protein NATD1; N-acetyltransferase domain containing 1	0.604
DHRS7B	PRR7	ENSP00000378887	ENSP00000327168	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Proline-rich protein 7; Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN. Might play a redundant role in the regulation of T cell receptor signaling. Might promote apoptosis in T cells	0.594
DHRS7B	RAB1B	ENSP00000378887	ENSP00000310226	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Ras-related protein Rab-1B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which t [...]	0.828
DHRS7B	RAB7A	ENSP00000378887	ENSP00000265062	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient- transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulat [...]	0.870
DHRS7B	SPATA2L	ENSP00000378887	ENSP00000289805	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Spermatogenesis-associated protein 2-like protein; Spermatogenesis associated 2 like	0.539
DHRS7B	TMEM11	ENSP00000378887	ENSP00000319992	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis; Belongs to the TMEM11 family	0.640
DNAJC8	DHRS7B	ENSP00000263697	ENSP00000378887	DnaJ homolog subfamily C member 8; Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells; DNAJ heat shock proteins	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	0.536
DNAJC8	PRR7	ENSP00000263697	ENSP00000327168	DnaJ homolog subfamily C member 8; Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells; DNAJ heat shock proteins	Proline-rich protein 7; Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN. Might play a redundant role in the regulation of T cell receptor signaling. Might promote apoptosis in T cells	0.531
GPATCH2L	DHRS7B	ENSP00000261530	ENSP00000378887	G patch domain-containing protein 2-like; G-patch domain containing 2 like	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	0.538
LRRC48	DHRS7B	ENSP00000382140	ENSP00000378887	Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	0.503
LRRC48	NATD1	ENSP00000382140	ENSP00000478388	Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility	Protein NATD1; N-acetyltransferase domain containing 1	0.601
LRRC48	TMEM11	ENSP00000382140	ENSP00000319992	Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility	Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis; Belongs to the TMEM11 family	0.402
NATD1	DHRS7B	ENSP00000478388	ENSP00000378887	Protein NATD1; N-acetyltransferase domain containing 1	Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	0.604
NATD1	LRRC48	ENSP00000478388	ENSP00000382140	Protein NATD1; N-acetyltransferase domain containing 1	Dynein regulatory complex subunit 3; Key component of the nexin-dynein regulatory complex (N- DRC), a key regulator of ciliary motility	0.601
NATD1	TMEM11	ENSP00000478388	ENSP00000319992	Protein NATD1; N-acetyltransferase domain containing 1	Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis; Belongs to the TMEM11 family	0.795

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