GPR135 protein (human) - STRING database

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GPR135

Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans (494 aa)

Predicted Functional Partners:

PTAFR

0.716

GPR141

0.668

GPR62

0.640

GPR142

0.639

TIMM9

0.629

FBXO34

0.628

GPR25

0.628

GPR162

0.609

OR6V1

0.570

PSMA3

0.569

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FBXO34	GPR135	ENSP00000313159	ENSP00000378548	F-box only protein 34; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	0.628
FBXO34	PSMA3	ENSP00000313159	ENSP00000216455	F-box only protein 34; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other	Proteasome subunit alpha type-3; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...]	0.576
FBXO34	TIMM9	ENSP00000313159	ENSP00000378588	F-box only protein 34; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other	Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space; Belongs to the small Tim family	0.638
GPR135	FBXO34	ENSP00000378548	ENSP00000313159	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	F-box only protein 34; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other	0.628
GPR135	GPR141	ENSP00000378548	ENSP00000390410	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans	0.668
GPR135	GPR142	ENSP00000378548	ENSP00000335158	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans	0.639
GPR135	GPR162	ENSP00000378548	ENSP00000311528	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans	0.609
GPR135	GPR25	ENSP00000378548	ENSP00000301917	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 25; Orphan receptor; G protein-coupled receptors, Class A orphans	0.628
GPR135	GPR62	ENSP00000378548	ENSP00000319250	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 62; Orphan receptor; G protein-coupled receptors, Class A orphans	0.640
GPR135	OR6V1	ENSP00000378548	ENSP00000396085	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Olfactory receptor 6V1; Odorant receptor; Olfactory receptors, family 6	0.570
GPR135	PSMA3	ENSP00000378548	ENSP00000216455	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Proteasome subunit alpha type-3; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...]	0.569
GPR135	PTAFR	ENSP00000378548	ENSP00000362965	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Platelet-activating factor receptor; Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth- muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol- calcium second messenger system	0.716
GPR135	TIMM9	ENSP00000378548	ENSP00000378588	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space; Belongs to the small Tim family	0.629
GPR141	GPR135	ENSP00000390410	ENSP00000378548	Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	0.668
GPR141	GPR142	ENSP00000390410	ENSP00000335158	Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans	0.826
GPR142	GPR135	ENSP00000335158	ENSP00000378548	Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	0.639
GPR142	GPR141	ENSP00000335158	ENSP00000390410	Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans	0.826
GPR142	GPR162	ENSP00000335158	ENSP00000311528	Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans	0.704
GPR142	GPR25	ENSP00000335158	ENSP00000301917	Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 25; Orphan receptor; G protein-coupled receptors, Class A orphans	0.400
GPR162	GPR135	ENSP00000311528	ENSP00000378548	Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans	0.609

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