node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC13 | CCDC18 | ENSP00000309836 | ENSP00000383808 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | Coiled-coil domain containing 18 | 0.789 |
CCDC13 | CCDC66 | ENSP00000309836 | ENSP00000378167 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | Coiled-coil domain containing 66 | 0.673 |
CCDC13 | CEP290 | ENSP00000309836 | ENSP00000448012 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. Required for the correct localization of ciliary and phototransduction proteins in retinal photorecepto [...] | 0.574 |
CCDC13 | KIAA0753 | ENSP00000309836 | ENSP00000355250 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | Protein moonraker; Involved in centriole duplication. Positively regulates CEP63 centrosomal localization. Required for WDR62 centrosomal localization and promotes the centrosomal localization of CDK2 | 0.652 |
CCDC13 | KIAA1377 | ENSP00000309836 | ENSP00000263468 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | Centrosomal protein of 126 kDa; Participates in cytokinesis. Necessary for microtubules and mitotic spindle organization. Involved in primary cilium formation | 0.678 |
CCDC13 | PIBF1 | ENSP00000309836 | ENSP00000317144 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 | 0.792 |
CCDC18 | CCDC13 | ENSP00000383808 | ENSP00000309836 | Coiled-coil domain containing 18 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | 0.789 |
CCDC18 | CCDC66 | ENSP00000383808 | ENSP00000378167 | Coiled-coil domain containing 18 | Coiled-coil domain containing 66 | 0.753 |
CCDC18 | CFAP36 | ENSP00000383808 | ENSP00000342699 | Coiled-coil domain containing 18 | Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family | 0.712 |
CCDC18 | KIAA0753 | ENSP00000383808 | ENSP00000355250 | Coiled-coil domain containing 18 | Protein moonraker; Involved in centriole duplication. Positively regulates CEP63 centrosomal localization. Required for WDR62 centrosomal localization and promotes the centrosomal localization of CDK2 | 0.678 |
CCDC18 | KIAA1377 | ENSP00000383808 | ENSP00000263468 | Coiled-coil domain containing 18 | Centrosomal protein of 126 kDa; Participates in cytokinesis. Necessary for microtubules and mitotic spindle organization. Involved in primary cilium formation | 0.683 |
CCDC18 | PIBF1 | ENSP00000383808 | ENSP00000317144 | Coiled-coil domain containing 18 | Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 | 0.682 |
CCDC66 | CCDC13 | ENSP00000378167 | ENSP00000309836 | Coiled-coil domain containing 66 | Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia | 0.673 |
CCDC66 | CCDC18 | ENSP00000378167 | ENSP00000383808 | Coiled-coil domain containing 66 | Coiled-coil domain containing 18 | 0.753 |
CCDC66 | CEP290 | ENSP00000378167 | ENSP00000448012 | Coiled-coil domain containing 66 | Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. Required for the correct localization of ciliary and phototransduction proteins in retinal photorecepto [...] | 0.709 |
CCDC66 | CFAP36 | ENSP00000378167 | ENSP00000342699 | Coiled-coil domain containing 66 | Cilia- and flagella-associated protein 36; May act as an effector for ARL3; Belongs to the CFAP36 family | 0.641 |
CCDC66 | KIAA0753 | ENSP00000378167 | ENSP00000355250 | Coiled-coil domain containing 66 | Protein moonraker; Involved in centriole duplication. Positively regulates CEP63 centrosomal localization. Required for WDR62 centrosomal localization and promotes the centrosomal localization of CDK2 | 0.616 |
CCDC66 | KIAA1377 | ENSP00000378167 | ENSP00000263468 | Coiled-coil domain containing 66 | Centrosomal protein of 126 kDa; Participates in cytokinesis. Necessary for microtubules and mitotic spindle organization. Involved in primary cilium formation | 0.682 |
CCDC66 | NXNL2 | ENSP00000378167 | ENSP00000365014 | Coiled-coil domain containing 66 | Nucleoredoxin-like protein 2; May be involved in the maintenance of both the function and the viability of sensory neurons, including photoreceptors and olfactory neurons; Nucleoredoxin family | 0.701 |
CCDC66 | PIBF1 | ENSP00000378167 | ENSP00000317144 | Coiled-coil domain containing 66 | Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 | 0.627 |