• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF454 ZNF454 OR4N5 OR4N5 LRRC24 LRRC24 TMEM132C TMEM132C GLI4 GLI4 PCDHGA2 PCDHGA2 C11orf80 C11orf80 CCDC85A CCDC85A PABPC5 PABPC5 OR4K14 OR4K14 TCTEX1D1 TCTEX1D1
"PCDHGA2" - Protocadherin gamma-A2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
PCDHGA2Protocadherin gamma-A2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (932 aa)    
Predicted Functional Partners:
OR4K14
Olfactory receptor 4K14; Odorant receptor; Olfactory receptors, family 4 (310 aa)
           
  0.578
OR4N5
Olfactory receptor 4N5; Odorant receptor; Olfactory receptors, family 4 (308 aa)
           
  0.548
C11orf80
Type 2 DNA topoisomerase 6 subunit B-like; Isoform 3- Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles (572 aa)
           
  0.515
LRRC24
Leucine-rich repeat-containing protein 24; Leucine rich repeat containing 24; I-set domain containing (513 aa)
           
  0.512
ZNF454
Zinc finger protein 454; May be involved in transcriptional regulation; Zinc fingers C2H2-type (522 aa)
       
 
  0.477
PABPC5
Polyadenylate-binding protein 5; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity); RNA binding motif containing (382 aa)
     
   
  0.468
CCDC85A
Coiled-coil domain containing 85A; Belongs to the CCDC85 family (553 aa)
     
   
  0.462
GLI4
GLI family zinc finger 4; Zinc fingers C2H2-type (376 aa)
       
 
  0.452
TMEM132C
Transmembrane protein 132C; Protein phosphatase 1 regulatory subunits (1108 aa)
     
   
  0.447
TCTEX1D1
Tctex1 domain containing 1; Belongs to the dynein light chain Tctex-type family (179 aa)
           
  0.447
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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