UTP14A protein (human) - STRING database

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UTP14A

U3 small nucleolar RNA-associated protein 14 homolog A; May be required for ribosome biogenesis (771 aa)

Predicted Functional Partners:

MPHOSPH10

0.999

DCAF13

0.999

NOP58

0.999

NOP56

0.998

DHX37

0.998

NOP14

0.998

FTSJ3

0.998

PDCD11

0.997

UTP6

0.997

UTP18

0.997

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCAF13	DHX37	ENSP00000297579	ENSP00000311135	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	0.991
DCAF13	FTSJ3	ENSP00000297579	ENSP00000396673	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily	0.989
DCAF13	MPHOSPH10	ENSP00000297579	ENSP00000244230	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; MPP10 subcomplex	0.998
DCAF13	NOP14	ENSP00000297579	ENSP00000405068	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity); Belongs to the NOP14 family	0.998
DCAF13	NOP56	ENSP00000297579	ENSP00000370589	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs; Belongs to the NOP5/NOP56 family	0.999
DCAF13	NOP58	ENSP00000297579	ENSP00000264279	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs; Belongs to the NOP5/NOP56 family	0.999
DCAF13	PDCD11	ENSP00000297579	ENSP00000358812	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA; Minor histocompatibility antigens	0.997
DCAF13	UTP14A	ENSP00000297579	ENSP00000377944	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	U3 small nucleolar RNA-associated protein 14 homolog A; May be required for ribosome biogenesis	0.999
DCAF13	UTP18	ENSP00000297579	ENSP00000225298	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA; UTPb subcomplex	0.999
DCAF13	UTP6	ENSP00000297579	ENSP00000261708	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA; UTPb subcomplex	0.999
DHX37	DCAF13	ENSP00000311135	ENSP00000297579	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors	0.991
DHX37	FTSJ3	ENSP00000311135	ENSP00000396673	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily	0.990
DHX37	MPHOSPH10	ENSP00000311135	ENSP00000244230	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; MPP10 subcomplex	0.997
DHX37	NOP14	ENSP00000311135	ENSP00000405068	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity); Belongs to the NOP14 family	0.996
DHX37	NOP56	ENSP00000311135	ENSP00000370589	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs; Belongs to the NOP5/NOP56 family	0.993
DHX37	NOP58	ENSP00000311135	ENSP00000264279	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs; Belongs to the NOP5/NOP56 family	0.995
DHX37	PDCD11	ENSP00000311135	ENSP00000358812	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA; Minor histocompatibility antigens	0.994
DHX37	UTP14A	ENSP00000311135	ENSP00000377944	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	U3 small nucleolar RNA-associated protein 14 homolog A; May be required for ribosome biogenesis	0.998
DHX37	UTP18	ENSP00000311135	ENSP00000225298	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA; UTPb subcomplex	0.993
DHX37	UTP6	ENSP00000311135	ENSP00000261708	Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37	U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA; UTPb subcomplex	0.994

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