• Version:
  • 11.0 [archived version]
STRINGSTRING
ANKRD49 ANKRD49 RNH1 RNH1 ASPH ASPH KLF7 KLF7 FBXO38 FBXO38 FBXO34 FBXO34 FBXO28 FBXO28 FBXO36 FBXO36 FBXO16 FBXO16 FBXO47 FBXO47 FBXO42 FBXO42
"FBXO38" - F-box only protein 38 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO38F-box only protein 38; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. May coactivate KLF7, but does not seem to promote KLF7 ubiquitination (By similarity); F-boxes other (1113 aa)    
Predicted Functional Partners:
KLF7
Krueppel-like factor 7; Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence; Kruppel like factors (302 aa)
       
 
  0.925
RNH1
Ribonuclease inhibitor; Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis (461 aa)
           
  0.800
FBXO42
F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation; F-boxes other (717 aa)
     
   
  0.774
FBXO36
F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other (188 aa)
           
  0.751
FBXO34
F-box only protein 34; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other (711 aa)
           
  0.728
FBXO16
F-box only protein 16; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other (292 aa)
           
  0.702
FBXO47
F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other (452 aa)
           
  0.695
FBXO28
F-box only protein 28; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other (368 aa)
           
  0.660
ASPH
Aspartyl/asparaginyl beta-hydroxylase; Isoform 1- specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins; Belongs to the aspartyl/asparaginyl beta-hydroxylase family (758 aa)
           
  0.653
ANKRD49
Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF- kappaB pathway (By similarity); Ankyrin repeat domain containing (239 aa)
           
  0.643
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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