node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AJAP1 | KRT222 | ENSP00000367433 | ENSP00000377616 | Adherens junction-associated protein 1; Plays a role in cell adhesion and cell migration | Keratin-like protein KRT222; Keratins, type II | 0.558 |
GALNT9 | KRT222 | ENSP00000380488 | ENSP00000377616 | Polypeptide N-acetylgalactosaminyltransferase 9; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3; Polypeptide N-acetylgalactosaminyltransferases | Keratin-like protein KRT222; Keratins, type II | 0.509 |
GALNT9 | ZNF808 | ENSP00000380488 | ENSP00000352846 | Polypeptide N-acetylgalactosaminyltransferase 9; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3; Polypeptide N-acetylgalactosaminyltransferases | Zinc finger protein 808; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.445 |
KRT222 | AJAP1 | ENSP00000377616 | ENSP00000367433 | Keratin-like protein KRT222; Keratins, type II | Adherens junction-associated protein 1; Plays a role in cell adhesion and cell migration | 0.558 |
KRT222 | GALNT9 | ENSP00000377616 | ENSP00000380488 | Keratin-like protein KRT222; Keratins, type II | Polypeptide N-acetylgalactosaminyltransferase 9; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3; Polypeptide N-acetylgalactosaminyltransferases | 0.509 |
KRT222 | KRTAP26-1 | ENSP00000377616 | ENSP00000353742 | Keratin-like protein KRT222; Keratins, type II | Keratin-associated protein 26-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the PMG family | 0.500 |
KRT222 | MRPL15 | ENSP00000377616 | ENSP00000260102 | Keratin-like protein KRT222; Keratins, type II | Mitochondrial ribosomal protein L15 | 0.555 |
KRT222 | SLC6A17 | ENSP00000377616 | ENSP00000330199 | Keratin-like protein KRT222; Keratins, type II | Sodium-dependent neutral amino acid transporter SLC6A17; Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity); Solute carriers | 0.584 |
KRT222 | SMARCD2 | ENSP00000377616 | ENSP00000392617 | Keratin-like protein KRT222; Keratins, type II | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation; Belongs to [...] | 0.692 |
KRT222 | SMARCE1 | ENSP00000377616 | ENSP00000323967 | Keratin-like protein KRT222; Keratins, type II | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). D [...] | 0.592 |
KRT222 | TACO1 | ENSP00000377616 | ENSP00000258975 | Keratin-like protein KRT222; Keratins, type II | Translational activator of cytochrome c oxidase 1; Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1; Belongs to the TACO1 family | 0.721 |
KRT222 | TNS4 | ENSP00000377616 | ENSP00000254051 | Keratin-like protein KRT222; Keratins, type II | Tensin-4; May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3; SH2 domain containing | 0.534 |
KRT222 | ZNF808 | ENSP00000377616 | ENSP00000352846 | Keratin-like protein KRT222; Keratins, type II | Zinc finger protein 808; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.510 |
KRTAP26-1 | KRT222 | ENSP00000353742 | ENSP00000377616 | Keratin-associated protein 26-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the PMG family | Keratin-like protein KRT222; Keratins, type II | 0.500 |
MRPL15 | KRT222 | ENSP00000260102 | ENSP00000377616 | Mitochondrial ribosomal protein L15 | Keratin-like protein KRT222; Keratins, type II | 0.555 |
SLC6A17 | KRT222 | ENSP00000330199 | ENSP00000377616 | Sodium-dependent neutral amino acid transporter SLC6A17; Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity); Solute carriers | Keratin-like protein KRT222; Keratins, type II | 0.584 |
SLC6A17 | TNS4 | ENSP00000330199 | ENSP00000254051 | Sodium-dependent neutral amino acid transporter SLC6A17; Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity); Solute carriers | Tensin-4; May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3; SH2 domain containing | 0.420 |
SMARCD2 | KRT222 | ENSP00000392617 | ENSP00000377616 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation; Belongs to [...] | Keratin-like protein KRT222; Keratins, type II | 0.692 |
SMARCD2 | SMARCE1 | ENSP00000392617 | ENSP00000323967 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation; Belongs to [...] | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). D [...] | 0.997 |
SMARCE1 | KRT222 | ENSP00000323967 | ENSP00000377616 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). D [...] | Keratin-like protein KRT222; Keratins, type II | 0.592 |