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  • 11.0 [archived version]
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GALNT9 GALNT9 SLC6A17 SLC6A17 ZNF808 ZNF808 TNS4 TNS4 AJAP1 AJAP1 KRT222 KRT222 KRTAP26-1 KRTAP26-1 MRPL15 MRPL15 TACO1 TACO1 SMARCD2 SMARCD2 SMARCE1 SMARCE1
"KRT222" - Keratin-like protein KRT222 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
KRT222Keratin-like protein KRT222; Keratins, type II (295 aa)    
Predicted Functional Partners:
TACO1
Translational activator of cytochrome c oxidase 1; Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1; Belongs to the TACO1 family (297 aa)
           
  0.721
SMARCD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation; Belongs to [...] (531 aa)
           
  0.692
SMARCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). D [...] (411 aa)
           
  0.592
SLC6A17
Sodium-dependent neutral amino acid transporter SLC6A17; Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity); Solute carriers (727 aa)
     
   
  0.584
AJAP1
Adherens junction-associated protein 1; Plays a role in cell adhesion and cell migration (411 aa)
     
   
  0.558
MRPL15
Mitochondrial ribosomal protein L15 (296 aa)
           
  0.555
TNS4
Tensin-4; May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3; SH2 domain containing (715 aa)
           
  0.534
ZNF808
Zinc finger protein 808; May be involved in transcriptional regulation; Zinc fingers C2H2-type (903 aa)
           
  0.510
GALNT9
Polypeptide N-acetylgalactosaminyltransferase 9; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3; Polypeptide N-acetylgalactosaminyltransferases (237 aa)
     
   
  0.509
KRTAP26-1
Keratin-associated protein 26-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the PMG family (210 aa)
           
  0.500
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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