node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAD2 | CCNJL | ENSP00000268624 | ENSP00000377547 | Adenosine deaminase domain containing 2; Adenosine deaminases acting on RNA | Cyclin-J-like protein; Cyclin J like; Cyclins | 0.554 |
CCNJL | ADAD2 | ENSP00000377547 | ENSP00000268624 | Cyclin-J-like protein; Cyclin J like; Cyclins | Adenosine deaminase domain containing 2; Adenosine deaminases acting on RNA | 0.554 |
CCNJL | CDC6 | ENSP00000377547 | ENSP00000209728 | Cyclin-J-like protein; Cyclin J like; Cyclins | Cell division control protein 6 homolog; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated | 0.585 |
CCNJL | GRTP1 | ENSP00000377547 | ENSP00000364579 | Cyclin-J-like protein; Cyclin J like; Cyclins | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s) | 0.549 |
CCNJL | HLF | ENSP00000377547 | ENSP00000226067 | Cyclin-J-like protein; Cyclin J like; Cyclins | Hepatic leukemia factor; HLF, PAR bZIP transcription factor; Belongs to the bZIP family. PAR subfamily | 0.537 |
CCNJL | MCM5 | ENSP00000377547 | ENSP00000216122 | Cyclin-J-like protein; Cyclin J like; Cyclins | DNA replication licensing factor MCM5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.629 |
CCNJL | MCM7 | ENSP00000377547 | ENSP00000307288 | Cyclin-J-like protein; Cyclin J like; Cyclins | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.527 |
CCNJL | OIT3 | ENSP00000377547 | ENSP00000333900 | Cyclin-J-like protein; Cyclin J like; Cyclins | Oncoprotein-induced transcript 3 protein; May be involved in hepatocellular function and development | 0.516 |
CCNJL | PARM1 | ENSP00000377547 | ENSP00000370224 | Cyclin-J-like protein; Cyclin J like; Cyclins | Prostate androgen-regulated mucin-like protein 1; May regulate TLP1 expression and telomerase activity, thus enabling certain prostatic cells to resist apoptosis | 0.526 |
CCNJL | TMTC2 | ENSP00000377547 | ENSP00000322300 | Cyclin-J-like protein; Cyclin J like; Cyclins | Transmembrane and tetratricopeptide repeat containing 2 | 0.557 |
CCNJL | TOMM34 | ENSP00000377547 | ENSP00000361900 | Cyclin-J-like protein; Cyclin J like; Cyclins | Mitochondrial import receptor subunit TOM34; Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state; Tetratricopeptide repeat domain containing | 0.649 |
CDC6 | CCNJL | ENSP00000209728 | ENSP00000377547 | Cell division control protein 6 homolog; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated | Cyclin-J-like protein; Cyclin J like; Cyclins | 0.585 |
CDC6 | MCM5 | ENSP00000209728 | ENSP00000216122 | Cell division control protein 6 homolog; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated | DNA replication licensing factor MCM5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
CDC6 | MCM7 | ENSP00000209728 | ENSP00000307288 | Cell division control protein 6 homolog; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
GRTP1 | CCNJL | ENSP00000364579 | ENSP00000377547 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s) | Cyclin-J-like protein; Cyclin J like; Cyclins | 0.549 |
HLF | CCNJL | ENSP00000226067 | ENSP00000377547 | Hepatic leukemia factor; HLF, PAR bZIP transcription factor; Belongs to the bZIP family. PAR subfamily | Cyclin-J-like protein; Cyclin J like; Cyclins | 0.537 |
MCM5 | CCNJL | ENSP00000216122 | ENSP00000377547 | DNA replication licensing factor MCM5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cyclin-J-like protein; Cyclin J like; Cyclins | 0.629 |
MCM5 | CDC6 | ENSP00000216122 | ENSP00000209728 | DNA replication licensing factor MCM5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein 6 homolog; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated | 0.999 |
MCM5 | MCM7 | ENSP00000216122 | ENSP00000307288 | DNA replication licensing factor MCM5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
MCM7 | CCNJL | ENSP00000307288 | ENSP00000377547 | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cyclin-J-like protein; Cyclin J like; Cyclins | 0.527 |