https://version11.string-db.org/cgi/show_network_section.pl?networkId=GgTm5SkXki2e
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There are several matches for 'ENSP00000377478'.
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organism
protein
Homo sapiens
MAGEA2B - Melanoma antigen family A, 2B; Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Also represses p73/TP73 activity. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal d [...]
[a.k.a. MAGEA2, MAGE2, MAGEA2A,
ENSP00000377478
]
Homo sapiens
MAGEA12 - Melanoma-associated antigen 12; Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines; MAGE family
[a.k.a. MAGE12, MAGEA12-202, MAGE-12 antigen,
ENSP00000377478
]
Homo sapiens
MAGEA3 - Melanoma-associated antigen 3; Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes; MA [...]
[a.k.a. MAGE3, Q6FHI6, BC011744,
ENSP00000377478
]