| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACTL9 | C7orf72 | ENSP00000316674 | ENSP00000297001 | Actin-like protein 9; Actin related proteins | Spermatogenesis-associated protein 48; Chromosome 7 open reading frame 72 | 0.512 |
| ACTL9 | CAPZA3 | ENSP00000316674 | ENSP00000326238 | Actin-like protein 9; Actin related proteins | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | 0.662 |
| ACTL9 | LRRC74A | ENSP00000316674 | ENSP00000377369 | Actin-like protein 9; Actin related proteins | Leucine-rich repeat-containing protein 74A; Leucine rich repeat containing 74A | 0.509 |
| AREL1 | FAM161B | ENSP00000348714 | ENSP00000286544 | Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation | Protein FAM161B; Family with sequence similarity 161 member B; Belongs to the FAM161 family | 0.734 |
| AREL1 | FCF1 | ENSP00000348714 | ENSP00000344393 | Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation | rRNA-processing protein FCF1 homolog; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly | 0.615 |
| AREL1 | LIN52 | ENSP00000348714 | ENSP00000451812 | Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation | Protein lin-52 homolog; Lin-52 DREAM MuvB core complex component | 0.487 |
| AREL1 | LRRC74A | ENSP00000348714 | ENSP00000377369 | Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation | Leucine-rich repeat-containing protein 74A; Leucine rich repeat containing 74A | 0.766 |
| AREL1 | PTGR2 | ENSP00000348714 | ENSP00000452280 | Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation | Prostaglandin reductase 2; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity) | 0.486 |
| AREL1 | VRTN | ENSP00000348714 | ENSP00000256362 | Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation | Vertnin; Vertebrae development associated; Belongs to the vertnin family | 0.574 |
| C7orf72 | ACTL9 | ENSP00000297001 | ENSP00000316674 | Spermatogenesis-associated protein 48; Chromosome 7 open reading frame 72 | Actin-like protein 9; Actin related proteins | 0.512 |
| C7orf72 | CAPZA3 | ENSP00000297001 | ENSP00000326238 | Spermatogenesis-associated protein 48; Chromosome 7 open reading frame 72 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | 0.521 |
| C7orf72 | LRRC74A | ENSP00000297001 | ENSP00000377369 | Spermatogenesis-associated protein 48; Chromosome 7 open reading frame 72 | Leucine-rich repeat-containing protein 74A; Leucine rich repeat containing 74A | 0.509 |
| CAPZA3 | ACTL9 | ENSP00000326238 | ENSP00000316674 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Actin-like protein 9; Actin related proteins | 0.662 |
| CAPZA3 | C7orf72 | ENSP00000326238 | ENSP00000297001 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Spermatogenesis-associated protein 48; Chromosome 7 open reading frame 72 | 0.521 |
| CAPZA3 | LRRC74A | ENSP00000326238 | ENSP00000377369 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Leucine-rich repeat-containing protein 74A; Leucine rich repeat containing 74A | 0.509 |
| FAM161B | AREL1 | ENSP00000286544 | ENSP00000348714 | Protein FAM161B; Family with sequence similarity 161 member B; Belongs to the FAM161 family | Apoptosis-resistant E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation | 0.734 |
| FAM161B | FCF1 | ENSP00000286544 | ENSP00000344393 | Protein FAM161B; Family with sequence similarity 161 member B; Belongs to the FAM161 family | rRNA-processing protein FCF1 homolog; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly | 0.713 |
| FAM161B | LIN52 | ENSP00000286544 | ENSP00000451812 | Protein FAM161B; Family with sequence similarity 161 member B; Belongs to the FAM161 family | Protein lin-52 homolog; Lin-52 DREAM MuvB core complex component | 0.705 |
| FAM161B | LRRC74A | ENSP00000286544 | ENSP00000377369 | Protein FAM161B; Family with sequence similarity 161 member B; Belongs to the FAM161 family | Leucine-rich repeat-containing protein 74A; Leucine rich repeat containing 74A | 0.783 |
| FAM161B | PTGR2 | ENSP00000286544 | ENSP00000452280 | Protein FAM161B; Family with sequence similarity 161 member B; Belongs to the FAM161 family | Prostaglandin reductase 2; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity) | 0.699 |
