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  • 11.0 [archived version]
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RASGEF1C RASGEF1C ZMYM1 ZMYM1 PHYHIPL PHYHIPL ZSWIM3 ZSWIM3 FRA10AC1 FRA10AC1 NCEH1 NCEH1 ZNF359 ZNF359 ZNF318 ZNF318 LHX4-AS1 LHX4-AS1 NOX4 NOX4 ANKRD7 ANKRD7
"ZNF359" - Zinc finger protein 23 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF359Zinc finger protein 23; May be involved in transcriptional regulation. May have a role in embryonic development; Belongs to the krueppel C2H2-type zinc-finger protein family (643 aa)    
Predicted Functional Partners:
NOX4
NADPH oxidase 4; Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and is [...] (578 aa)
           
  0.759
LHX4-AS1
Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18-1-CoA, lower affinity for unsaturated C20-4-CoA, and very weak affinity for saturated C16-0- CoA. Does not bind fatty acids (282 aa)
           
  0.605
ZNF318
Zinc finger protein 318; Repressed AR-mediated transcriptional activation. May act as a transcriptional regulator during spermatogenesis and, in particular, during meiotic division (By similarity); Zinc fingers C2H2-type (2279 aa)
           
  0.534
FRA10AC1
Protein FRA10AC1; FRA10A associated CGG repeat 1; Spliceosomal C complex (315 aa)
           
  0.499
ANKRD7
Ankyrin repeat domain-containing protein 7; Ankyrin repeat domain containing (254 aa)
     
 
  0.488
RASGEF1C
Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF) (466 aa)
       
 
  0.450
ZSWIM3
Zinc finger SWIM-type containing 3 (696 aa)
           
  0.442
PHYHIPL
Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system; Fibronectin type III domain containing (376 aa)
           
  0.440
NCEH1
Neutral cholesterol ester hydrolase 1; Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration (448 aa)
       
 
  0.439
ZMYM1
Zinc finger MYM-type containing 1 (1142 aa)
           
  0.438
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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