| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP4B1 | BCL2L15 | ENSP00000358582 | ENSP00000376992 | AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper as [...] | Bcl-2-like protein 15; BCL2 like 15 | 0.537 |
| AP4B1 | PHTF1 | ENSP00000358582 | ENSP00000358617 | AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper as [...] | Putative homeodomain transcription factor 1; May play a role in transcription regulation | 0.596 |
| AP4B1 | RSBN1 | ENSP00000358582 | ENSP00000261441 | AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper as [...] | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated ’Lys-20’ of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family | 0.549 |
| BCL2L1 | BCL2L14 | ENSP00000302564 | ENSP00000309132 | Bcl-2-like protein 1; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis; Belongs to the Bcl-2 family | Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family | 0.708 |
| BCL2L1 | BCL2L15 | ENSP00000302564 | ENSP00000376992 | Bcl-2-like protein 1; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis; Belongs to the Bcl-2 family | Bcl-2-like protein 15; BCL2 like 15 | 0.547 |
| BCL2L14 | BCL2L1 | ENSP00000309132 | ENSP00000302564 | Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family | Bcl-2-like protein 1; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis; Belongs to the Bcl-2 family | 0.708 |
| BCL2L14 | BCL2L15 | ENSP00000309132 | ENSP00000376992 | Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family | Bcl-2-like protein 15; BCL2 like 15 | 0.753 |
| BCL2L15 | AP4B1 | ENSP00000376992 | ENSP00000358582 | Bcl-2-like protein 15; BCL2 like 15 | AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper as [...] | 0.537 |
| BCL2L15 | BCL2L1 | ENSP00000376992 | ENSP00000302564 | Bcl-2-like protein 15; BCL2 like 15 | Bcl-2-like protein 1; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis; Belongs to the Bcl-2 family | 0.547 |
| BCL2L15 | BCL2L14 | ENSP00000376992 | ENSP00000309132 | Bcl-2-like protein 15; BCL2 like 15 | Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family | 0.753 |
| BCL2L15 | C3orf14 | ENSP00000376992 | ENSP00000418086 | Bcl-2-like protein 15; BCL2 like 15 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | 0.541 |
| BCL2L15 | FRRS1 | ENSP00000376992 | ENSP00000287474 | Bcl-2-like protein 15; BCL2 like 15 | Ferric-chelate reductase 1; Ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm; Belongs to the FRRS1 family | 0.531 |
| BCL2L15 | MANF | ENSP00000376992 | ENSP00000432799 | Bcl-2-like protein 15; BCL2 like 15 | Mesencephalic astrocyte-derived neurotrophic factor; Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death | 0.685 |
| BCL2L15 | MRPL50 | ENSP00000376992 | ENSP00000363999 | Bcl-2-like protein 15; BCL2 like 15 | Mitochondrial ribosomal protein L50 | 0.541 |
| BCL2L15 | PHTF1 | ENSP00000376992 | ENSP00000358617 | Bcl-2-like protein 15; BCL2 like 15 | Putative homeodomain transcription factor 1; May play a role in transcription regulation | 0.621 |
| BCL2L15 | RSBN1 | ENSP00000376992 | ENSP00000261441 | Bcl-2-like protein 15; BCL2 like 15 | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated ’Lys-20’ of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family | 0.566 |
| BCL2L15 | ZNF398 | ENSP00000376992 | ENSP00000420418 | Bcl-2-like protein 15; BCL2 like 15 | Zinc finger protein 398; Function as a transcriptional activator; Zinc fingers C2H2-type | 0.556 |
| C3orf14 | BCL2L15 | ENSP00000418086 | ENSP00000376992 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Bcl-2-like protein 15; BCL2 like 15 | 0.541 |
| C3orf14 | MRPL50 | ENSP00000418086 | ENSP00000363999 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Mitochondrial ribosomal protein L50 | 0.621 |
| FRRS1 | BCL2L15 | ENSP00000287474 | ENSP00000376992 | Ferric-chelate reductase 1; Ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm; Belongs to the FRRS1 family | Bcl-2-like protein 15; BCL2 like 15 | 0.531 |
